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  1. The aim of this study was to investigate the potential use of renal ultrasonography radiomics features in the histologic classification of glomerulopathy.

    Authors: Lijie Zhang, Zhengguang Chen, Lei Feng, Liwei Guo, Dong Liu, Jinjin Hai, Kai Qiao, Jian Chen, Bin Yan and Genyang Cheng

    Citation: BMC Medical Imaging 2021 21:115

    Content type: Research article

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  2. Arterial brain vessel segmentation allows utilising clinically relevant information contained within the cerebral vascular tree. Currently, however, no standardised performance measure is available to evaluate...

    Authors: Orhun Utku Aydin, Abdel Aziz Taha, Adam Hilbert, Ahmed A. Khalil, Ivana Galinovic, Jochen B. Fiebach, Dietmar Frey and Vince Istvan Madai

    Citation: BMC Medical Imaging 2021 21:113

    Content type: Research

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  3. Lung region segmentation is an important stage of automated image-based approaches for the diagnosis of respiratory diseases. Manual methods executed by experts are considered the gold standard, but it is time...

    Authors: Michael Osadebey, Hilde K. Andersen, Dag Waaler, Kristian Fossaa, Anne C. T. Martinsen and Marius Pedersen

    Citation: BMC Medical Imaging 2021 21:112

    Content type: Research article

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  4. In medical diagnosis of brain, the role of multi-modal medical image fusion is becoming more prominent. Among them, there is no lack of filtering layered fusion and newly emerging deep learning algorithms. The...

    Authors: Kai Guo, Xiongfei Li, Xiaohan Hu, Jichen Liu and Tiehu Fan

    Citation: BMC Medical Imaging 2021 21:111

    Content type: Research

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  5. For the treatment of radicular pain, nerve root infiltrations can be performed under MRI guidance in select, typically younger, patients where repeated CT exams are not desirable due to associated radiation ri...

    Authors: Max Scheffler, Pauline Coralie Guillemin, Orane Lorton, Enrique Maturana, Nicolas Lauper, Dennis E. Dominguez, Sylvain Terraz, Pierre-Alexandre Poletti, Rares Salomir and Sana Boudabbous

    Citation: BMC Medical Imaging 2021 21:110

    Content type: Technical advance

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  6. Glioma is a malignant brain tumor; its location is complex and is difficult to remove surgically. To diagnosis the brain tumor, doctors can precisely diagnose and localize the disease using medical images. How...

    Authors: Chih-Wei Lin, Yu Hong and Jinfu Liu

    Citation: BMC Medical Imaging 2021 21:109

    Content type: Technical advance

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  7. To evaluate the performance of a Deep Learning Image Reconstruction (DLIR) algorithm in pediatric head CT for improving image quality and lesion detection with 0.625 mm thin-slice images.

    Authors: Jihang Sun, Haoyan Li, Bei Wang, Jianying Li, Michelle Li, Zuofu Zhou and Yun Peng

    Citation: BMC Medical Imaging 2021 21:108

    Content type: Research article

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  8. To develop a regression neural network for the reconstruction of lesion probability maps on Magnetic Resonance Fingerprinting using echo-planar imaging (MRF-EPI) in addition to ...

    Authors: Ingo Hermann, Alena K. Golla, Eloy Martínez-Heras, Ralf Schmidt, Elisabeth Solana, Sara Llufriu, Achim Gass, Lothar R. Schad and Frank G. Zöllner

    Citation: BMC Medical Imaging 2021 21:107

    Content type: Technical advance

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  9. The amount of muscle volume (MV) varies between individuals and is important for health, well-being and performance. Therefore, the monitoring of MV using different imaging modalities is important. Magnetic re...

    Authors: Rasmus Liegnell, Fredrik Wessman, Adel Shalabi and Marita Harringe

    Citation: BMC Medical Imaging 2021 21:106

    Content type: Research article

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  10. In majority of studies on speckle tracking echocardiography (STE) the strain estimates are averaged over large areas of the left ventricle. This may impair the diagnostic capability of the STE in the case of e...

    Authors: Jakub Żmigrodzki, Szymon Cygan and Krzysztof Kałużyński

    Citation: BMC Medical Imaging 2021 21:105

    Content type: Research

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  11. This study prospectively investigates the agreement between radial (r-US) and meander-like (m-US) breast ultrasound with regard to lesion location, lesion size, morphological characteristics and final BI-RADS ...

    Authors: Pascale Brasier-Lutz, Claudia Jäggi-Wickes, Sabine Schaedelin, Rosemarie Burian, Cora-Ann Schoenenberger and Rosanna Zanetti-Dällenbach

    Citation: BMC Medical Imaging 2021 21:104

    Content type: Research article

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  12. Neonatal hyperbilirubinemia is a common clinical condition that requires medical attention in newborns, which may develop into acute bilirubin encephalopathy with a significant risk of long-term neurological d...

    Authors: Miao Wu, Xiaoxia Shen, Can Lai, Weihao Zheng, Yingqun Li, Zhongli Shangguan, Chuanbo Yan, Tingting Liu and Dan Wu

    Citation: BMC Medical Imaging 2021 21:103

    Content type: Research article

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  13. The aim of this study was to investigate the concordance in lesion detection, between conventional Handhold Ultrasound (HHUS) and The Anatomical Intelligence for Breast ultrasound scan method.

    Authors: Juan Li, Hao Wang, Lu Wang, Ting Wei, Minggang Wu, Tingting Li, Jifen Liao, Bo Tan and Man Lu

    Citation: BMC Medical Imaging 2021 21:102

    Content type: Research

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  14. Segmentation of the left atrium (LA) is required to evaluate atrial size and function, which are important imaging biomarkers for a wide range of cardiovascular conditions, such as atrial fibrillation, stroke,...

    Authors: Ricardo A. Gonzales, Felicia Seemann, Jérôme Lamy, Per M. Arvidsson, Einar Heiberg, Victor Murray and Dana C. Peters

    Citation: BMC Medical Imaging 2021 21:101

    Content type: Research

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  15. Nuclear protein Ki-67 indicates the status of cell proliferation and has been regarded as an attractive biomarker for the prognosis of HCC. The aim of this study is to investigate which radiomics model derived...

    Authors: Yanfen Fan, Yixing Yu, Ximing Wang, Mengjie Hu and Chunhong Hu

    Citation: BMC Medical Imaging 2021 21:100

    Content type: Research article

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  16. Whole-body diffusion-weighted imaging (WB-DWI) is a method for evaluating bone marrow infiltration in multiple myeloma (MM). This study seeks to elucidate the correlation between the apparent diffusion coeffic...

    Authors: Bei Zhang, Bingyang Bian, Zhiwei Zhao, Fang Lin, Zining Zhu and Mingwu Lou

    Citation: BMC Medical Imaging 2021 21:98

    Content type: Research article

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  17. Conventional dynamic contrast enhanced (DCE) magnetic resonance (MR) hardly achieves a good imaging performance of arteries and lymph nodes in the breast area. Therefore, a new imaging method is needed for the...

    Authors: Yang Liu, Jiaxin Hou, Zhijun Zhu, Bingguang Liu, Manrui Cao and Wenjian Qin

    Citation: BMC Medical Imaging 2021 21:97

    Content type: Research

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  18. Artificial Intelligence (AI) is a promising tool for cardiothoracic ratio (CTR) measurement that has been technically validated but not clinically evaluated on a large dataset. We observed and validated AI and...

    Authors: Pairash Saiviroonporn, Kanchanaporn Rodbangyang, Trongtum Tongdee, Warasinee Chaisangmongkon, Pakorn Yodprom, Thanogchai Siriapisith, Suwimon Wonglaksanapimon and Phakphoom Thiravit

    Citation: BMC Medical Imaging 2021 21:95

    Content type: Research

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  19. Mobile 3-dimensional fluoroscopes are an integral part of modern neurosurgical operating theatres and can also be used in combination with free available image post processing to depict cerebral vessels. In pr...

    Authors: Thomas Linsenmann, Andrea Cattaneo, Alexander März, Judith Weiland, Christian Stetter, Robert Nickl and Thomas Westermaier

    Citation: BMC Medical Imaging 2021 21:94

    Content type: Research article

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  20. In patients with peripheral artery disease (PAD), run-off MR-angiography (MRA) is a commonly performed diagnostic test to obtain high-resolution images for evaluation of the arterial system from the aorta thro...

    Authors: Felix Streckenbach, Felix G. Meinel, Felix Ammermann, Anke Busse, Andreas Neumann, Thomas Heller, Marc-André Weber and Ebba Beller

    Citation: BMC Medical Imaging 2021 21:93

    Content type: Research article

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  21. Differential diagnosis of tumour recurrence (TuR) from treatment effects (TrE), mostly induced by radiotherapy and chemotherapy, is still difficult by using conventional computed tomography (CT) or magnetic re...

    Authors: Cong Li, Chang Yi, Yingshen Chen, Shaoyan Xi, Chengcheng Guo, Qunying Yang, Jian Wang, Ke Sai, Ji Zhang, Chao Ke, Fanfan Chen, Yanchun Lv, Xiangsong Zhang and Zhongping Chen

    Citation: BMC Medical Imaging 2021 21:92

    Content type: Research article

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  22. To compare the quality of free-text reports (FTR) and structured reports (SR) of brain magnetic resonance imaging (MRI) examinations in patients following mechanical thrombectomy for acute stroke treatment.

    Authors: Sebastian Mönch, Tiberiu Andrisan, Kathleen Bernkopf, Benno Ikenberg, Benjamin Friedrich, Claus Zimmer and Dennis M. Hedderich

    Citation: BMC Medical Imaging 2021 21:91

    Content type: Research

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  23. Dynamic PET with kinetic modeling was reported to be potentially helpful in the assessment of hepatic malignancy. In this study, a kinetic modeling analysis was performed on hepatocellular carcinoma (HCC) and ...

    Authors: Jingnan Wang, Yunwen Shao, Bowei Liu, Xuezhu Wang, Barbara Katharina Geist, Xiang Li, Fang Li, Haitao Zhao, Marcus Hacker, Haiyan Ding, Hui Zhang and Li Huo

    Citation: BMC Medical Imaging 2021 21:90

    Content type: Research

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  24. The study compared clinical decisions regarding root angulation correction and root proximity based on the interpretation of Panoramic (PAN) versus Cone-Beam Computed Tomography (CBCT) images.

    Authors: Athbi Alqareer, Rania Nada, Aref Ghayyath, Mariam Baghdady and Veerasathpurush Allareddy

    Citation: BMC Medical Imaging 2021 21:89

    Content type: Research

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  25. MR fingerprinting (MRF) is a novel imaging method proposed for the diagnosis of Multiple Sclerosis (MS). This study aims to determine if MR Fingerprinting (MRF) relaxometry can differentiate frontal normal app...

    Authors: Thomaz R. Mostardeiro, Ananya Panda, Norbert G. Campeau, Robert J. Witte, Nicholas B. Larson, Yi Sui, Aiming Lu and Kiaran P. McGee

    Citation: BMC Medical Imaging 2021 21:88

    Content type: Research

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  26. Primary hyperparathyroidism (PHPT) results from an excess of parathyroid hormone (PTH) produced from an overactive parathyroid gland. The study aimed to explore the sonographic features of parathyroid adenomas...

    Authors: Ruigang Lu, Wei Zhao, Li Yin, Ruijun Guo, Bojun Wei, Mulan Jin, Xiang Zhou, Chun Zhang and Xiuzhang Lv

    Citation: BMC Medical Imaging 2021 21:87

    Content type: Research

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  27. The aim of this study was to evaluate the success of the artificial intelligence (AI) system in implant planning using three-dimensional cone-beam computed tomography (CBCT) images.

    Authors: Sevda Kurt Bayrakdar, Kaan Orhan, Ibrahim Sevki Bayrakdar, Elif Bilgir, Matvey Ezhov, Maxim Gusarev and Eugene Shumilov

    Citation: BMC Medical Imaging 2021 21:86

    Content type: Research

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  28. Pericardial hematoma is blood accumulation in the pericardial space. Although rare, it could arise in various conditions, such as after cardiac surgery. Clinical diagnosis of pericardial hematoma is implausibl...

    Authors: Aninka Saboe, Ferdy Sanjaya, Raden Erwin Affandi Soeriadi, Euis Maryani, Nuraini Yasmin Kusumawardhani, Charlotte Johanna Cool and Astri Astuti

    Citation: BMC Medical Imaging 2021 21:85

    Content type: Case report

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  29. The molecular biomarkers of breast ductal carcinoma in situ (DCIS) have important guiding significance for individualized precision treatment. This study was intended to explore the significance of radiomics b...

    Authors: Linyong Wu, Yujia Zhao, Peng Lin, Hui Qin, Yichen Liu, Da Wan, Xin Li, Yun He and Hong Yang

    Citation: BMC Medical Imaging 2021 21:84

    Content type: Research

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  30. The purpose of this study was to review our institutional experience with the EOS machine in order to identify the incidence and clinical significance of incidental extraspinal findings (IESF) in an adult spin...

    Authors: Lily Wood, Christopher Martin, David Polly, Samuel Luchsinger and Takashi Takahashi

    Citation: BMC Medical Imaging 2021 21:83

    Content type: Research article

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  31. Necrotic pulmonary lesions manifest as relatively low-density internally on contrast-enhanced computed tomography (CT). However, using CT to differentiate malignant and benign necrotic pulmonary lesions is cha...

    Authors: Qi Li, Xiao Fan, Tian-You Luo, Fa-Jin Lv and Xing-Tao Huang

    Citation: BMC Medical Imaging 2021 21:81

    Content type: Research

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  32. Primary retroperitoneal serous adenocarcinoma (PRSA) is a rare malignant disease. Given the rarity of the disease, the imaging features of PRSA are unclear. Contrast-enhanced ultrasound (CEUS) also plays an im...

    Authors: Lin-Yu Zhou, Xiao-Dan Zhu, Jian Jiang, Yan-Feng Bai and Tian-An Jiang

    Citation: BMC Medical Imaging 2021 21:80

    Content type: Case report

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  33. Functional lung MRI techniques are usually associated with time-consuming post-processing, where manual lung segmentation represents the most cumbersome part. The aim of this study was to investigate whether d...

    Authors: Andreas M. Weng, Julius F. Heidenreich, Corona Metz, Simon Veldhoen, Thorsten A. Bley and Tobias Wech

    Citation: BMC Medical Imaging 2021 21:79

    Content type: Research

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  34. One challenge to train deep convolutional neural network (CNNs) models with whole slide images (WSIs) is providing the required large number of costly, manually annotated image regions. Strategies to alleviate...

    Authors: Sebastian Otálora, Niccolò Marini, Henning Müller and Manfredo Atzori

    Citation: BMC Medical Imaging 2021 21:77

    Content type: Research

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  35. Evidence of diastolic dysfunction (DD) required for the diagnosis of heart failure with preserved ejection fraction (HFpEF) is elusive in atrial fibrillation (AF). Left ventricular (LV) and left atrial (LA) sp...

    Authors: Assaf Ben-Arzi, Evgeni Hazanov, Diab Ghanim, Guy Rozen, Ibrahim Marai, Liza Grosman-Rimon, Erez Kachel, Offer Amir and Shemy Carasso

    Citation: BMC Medical Imaging 2021 21:76

    Content type: Research article

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  36. Multiple guidelines for pancreatic ductal adenocarcinoma (PDAC) suggest that all stages of patients need to receive postoperative adjuvant chemotherapy. S-1 is a recently emerged oral antitumour agent recommen...

    Authors: Liang Liang, Ying Ding, Yiyi Yu, Kai Liu, Shengxiang Rao, Yingqian Ge and Mengsu Zeng

    Citation: BMC Medical Imaging 2021 21:75

    Content type: Research article

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  37. The EU gadolinium-based contrast agents (GBCA) market has changed in recent years due to the European Medicines Agency decision to suspend the marketing authorisation of linear GBCA and the marketing authorisa...

    Authors: Jarl Åsbjørn Jakobsen, Carlo Cosimo Quattrocchi, Frank H. H. Müller, Olivier Outteryck, Andrés Alcázar, Wolfgang Reith, Patricia Fraga, Valeria Panebianco, Alexis Sampedro and Radoslaw Pietura

    Citation: BMC Medical Imaging 2021 21:74

    Content type: Research article

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  38. To explore if the quantitative perfusion histogram parameters of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) correlates with the expression of PTEN, P-Akt and m-TOR protein in lung cancer.

    Authors: Bingqian Zhang, Zhenhua Zhao, Ya’nan Huang, Haijia Mao, Mingyue Zou, Cheng Wang, Guangmao Yu and Minming Zhang

    Citation: BMC Medical Imaging 2021 21:73

    Content type: Research article

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  39. Cardiac lipoma is a rare primary tumor in the heart and pericardium. Multimodality imaging methods, especially magnetic resonance imaging (MRI), are crucial in detecting and diagnosing cardiac lipomas. Besides...

    Authors: Shenglei Shu, Hongliang Yuan, Xiangchuang Kong, Jiazheng Wang, Jing Wang and Chuansheng Zheng

    Citation: BMC Medical Imaging 2021 21:71

    Content type: Research

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  40. Brain metastases are particularly common in patients with small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), with NSCLC showing a less  aggressive clinical course and lower chemo- and radio ...

    Authors: Sebastian Johannes Müller, Eya Khadhraoui, Nicole E. Neef, Christian Heiner Riedel and Marielle Ernst

    Citation: BMC Medical Imaging 2021 21:70

    Content type: Research article

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  41. In oncology, the correct determination of nodal metastatic disease is essential for patient management, as patient treatment and prognosis are closely linked to the stage of the disease. The aim of the study w...

    Authors: Andra-Iza Iuga, Heike Carolus, Anna J. Höink, Tom Brosch, Tobias Klinder, David Maintz, Thorsten Persigehl, Bettina Baeßler and Michael Püsken

    Citation: BMC Medical Imaging 2021 21:69

    Content type: Research article

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  42. Pediatric patients with liver disease require noninvasive monitoring to evaluate the risk of fibrosis progression. This study aimed to identify the significant factors affecting liver stiffness values using tw...

    Authors: Seunghyun Lee, Young Hun Choi, Yeon Jin Cho, Seul Bi Lee, Jung-Eun Cheon, Woo Sun Kim, Jae Sung Ko, Jaemoon Koh and Gyeong Hoon Kang

    Citation: BMC Medical Imaging 2021 21:68

    Content type: Research

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  43. ASPECTS scoring method varies, but which one is most suitable for predicting the prognosis still unclear. We aimed to evaluate the diagnostic performance of Automated (Auto)-, noncontrast CT (NCCT)- and CT per...

    Authors: Tiegong Wang, Luguang Chen, Xianglan Jin, Yuan Yuan, Qianwen Zhang, Chengwei Shao and Jianping Lu

    Citation: BMC Medical Imaging 2021 21:67

    Content type: Research

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  44. Reidentification of prior nodules for temporal comparison is an important but time-consuming step in lung cancer screening. We develop and evaluate an automated nodule detector that utilizes the axial-slice nu...

    Authors: Yeshwant Reddy Chillakuru, Kyle Kranen, Vishnu Doppalapudi, Zhangyuan Xiong, Letian Fu, Aarash Heydari, Aditya Sheth, Youngho Seo, Thienkhai Vu and Jae Ho Sohn

    Citation: BMC Medical Imaging 2021 21:66

    Content type: Research

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