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  1. MR fingerprinting (MRF) is a novel imaging method proposed for the diagnosis of Multiple Sclerosis (MS). This study aims to determine if MR Fingerprinting (MRF) relaxometry can differentiate frontal normal app...

    Authors: Thomaz R. Mostardeiro, Ananya Panda, Norbert G. Campeau, Robert J. Witte, Nicholas B. Larson, Yi Sui, Aiming Lu and Kiaran P. McGee
    Citation: BMC Medical Imaging 2021 21:88

    The Correction to this article has been published in BMC Medical Imaging 2021 21:137

  2. Primary hyperparathyroidism (PHPT) results from an excess of parathyroid hormone (PTH) produced from an overactive parathyroid gland. The study aimed to explore the sonographic features of parathyroid adenomas...

    Authors: Ruigang Lu, Wei Zhao, Li Yin, Ruijun Guo, Bojun Wei, Mulan Jin, Xiang Zhou, Chun Zhang and Xiuzhang Lv
    Citation: BMC Medical Imaging 2021 21:87
  3. The aim of this study was to evaluate the success of the artificial intelligence (AI) system in implant planning using three-dimensional cone-beam computed tomography (CBCT) images.

    Authors: Sevda Kurt Bayrakdar, Kaan Orhan, Ibrahim Sevki Bayrakdar, Elif Bilgir, Matvey Ezhov, Maxim Gusarev and Eugene Shumilov
    Citation: BMC Medical Imaging 2021 21:86
  4. Pericardial hematoma is blood accumulation in the pericardial space. Although rare, it could arise in various conditions, such as after cardiac surgery. Clinical diagnosis of pericardial hematoma is implausibl...

    Authors: Aninka Saboe, Ferdy Sanjaya, Raden Erwin Affandi Soeriadi, Euis Maryani, Nuraini Yasmin Kusumawardhani, Charlotte Johanna Cool and Astri Astuti
    Citation: BMC Medical Imaging 2021 21:85
  5. The molecular biomarkers of breast ductal carcinoma in situ (DCIS) have important guiding significance for individualized precision treatment. This study was intended to explore the significance of radiomics b...

    Authors: Linyong Wu, Yujia Zhao, Peng Lin, Hui Qin, Yichen Liu, Da Wan, Xin Li, Yun He and Hong Yang
    Citation: BMC Medical Imaging 2021 21:84
  6. The purpose of this study was to review our institutional experience with the EOS machine in order to identify the incidence and clinical significance of incidental extraspinal findings (IESF) in an adult spin...

    Authors: Lily Wood, Christopher Martin, David Polly, Samuel Luchsinger and Takashi Takahashi
    Citation: BMC Medical Imaging 2021 21:83
  7. Necrotic pulmonary lesions manifest as relatively low-density internally on contrast-enhanced computed tomography (CT). However, using CT to differentiate malignant and benign necrotic pulmonary lesions is cha...

    Authors: Qi Li, Xiao Fan, Tian-You Luo, Fa-Jin Lv and Xing-Tao Huang
    Citation: BMC Medical Imaging 2021 21:81
  8. Primary retroperitoneal serous adenocarcinoma (PRSA) is a rare malignant disease. Given the rarity of the disease, the imaging features of PRSA are unclear. Contrast-enhanced ultrasound (CEUS) also plays an im...

    Authors: Lin-Yu Zhou, Xiao-Dan Zhu, Jian Jiang, Yan-Feng Bai and Tian-An Jiang
    Citation: BMC Medical Imaging 2021 21:80
  9. Functional lung MRI techniques are usually associated with time-consuming post-processing, where manual lung segmentation represents the most cumbersome part. The aim of this study was to investigate whether d...

    Authors: Andreas M. Weng, Julius F. Heidenreich, Corona Metz, Simon Veldhoen, Thorsten A. Bley and Tobias Wech
    Citation: BMC Medical Imaging 2021 21:79
  10. One challenge to train deep convolutional neural network (CNNs) models with whole slide images (WSIs) is providing the required large number of costly, manually annotated image regions. Strategies to alleviate...

    Authors: Sebastian Otálora, Niccolò Marini, Henning Müller and Manfredo Atzori
    Citation: BMC Medical Imaging 2021 21:77
  11. Evidence of diastolic dysfunction (DD) required for the diagnosis of heart failure with preserved ejection fraction (HFpEF) is elusive in atrial fibrillation (AF). Left ventricular (LV) and left atrial (LA) sp...

    Authors: Assaf Ben-Arzi, Evgeni Hazanov, Diab Ghanim, Guy Rozen, Ibrahim Marai, Liza Grosman-Rimon, Erez Kachel, Offer Amir and Shemy Carasso
    Citation: BMC Medical Imaging 2021 21:76
  12. Multiple guidelines for pancreatic ductal adenocarcinoma (PDAC) suggest that all stages of patients need to receive postoperative adjuvant chemotherapy. S-1 is a recently emerged oral antitumour agent recommen...

    Authors: Liang Liang, Ying Ding, Yiyi Yu, Kai Liu, Shengxiang Rao, Yingqian Ge and Mengsu Zeng
    Citation: BMC Medical Imaging 2021 21:75
  13. The EU gadolinium-based contrast agents (GBCA) market has changed in recent years due to the European Medicines Agency decision to suspend the marketing authorisation of linear GBCA and the marketing authorisa...

    Authors: Jarl Åsbjørn Jakobsen, Carlo Cosimo Quattrocchi, Frank H. H. Müller, Olivier Outteryck, Andrés Alcázar, Wolfgang Reith, Patricia Fraga, Valeria Panebianco, Alexis Sampedro and Radoslaw Pietura
    Citation: BMC Medical Imaging 2021 21:74
  14. To explore if the quantitative perfusion histogram parameters of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) correlates with the expression of PTEN, P-Akt and m-TOR protein in lung cancer.

    Authors: Bingqian Zhang, Zhenhua Zhao, Ya’nan Huang, Haijia Mao, Mingyue Zou, Cheng Wang, Guangmao Yu and Minming Zhang
    Citation: BMC Medical Imaging 2021 21:73
  15. Cardiac lipoma is a rare primary tumor in the heart and pericardium. Multimodality imaging methods, especially magnetic resonance imaging (MRI), are crucial in detecting and diagnosing cardiac lipomas. Besides...

    Authors: Shenglei Shu, Hongliang Yuan, Xiangchuang Kong, Jiazheng Wang, Jing Wang and Chuansheng Zheng
    Citation: BMC Medical Imaging 2021 21:71
  16. Brain metastases are particularly common in patients with small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), with NSCLC showing a less  aggressive clinical course and lower chemo- and radio ...

    Authors: Sebastian Johannes Müller, Eya Khadhraoui, Nicole E. Neef, Christian Heiner Riedel and Marielle Ernst
    Citation: BMC Medical Imaging 2021 21:70
  17. In oncology, the correct determination of nodal metastatic disease is essential for patient management, as patient treatment and prognosis are closely linked to the stage of the disease. The aim of the study w...

    Authors: Andra-Iza Iuga, Heike Carolus, Anna J. Höink, Tom Brosch, Tobias Klinder, David Maintz, Thorsten Persigehl, Bettina Baeßler and Michael Püsken
    Citation: BMC Medical Imaging 2021 21:69
  18. Pediatric patients with liver disease require noninvasive monitoring to evaluate the risk of fibrosis progression. This study aimed to identify the significant factors affecting liver stiffness values using tw...

    Authors: Seunghyun Lee, Young Hun Choi, Yeon Jin Cho, Seul Bi Lee, Jung-Eun Cheon, Woo Sun Kim, Jae Sung Ko, Jaemoon Koh and Gyeong Hoon Kang
    Citation: BMC Medical Imaging 2021 21:68
  19. ASPECTS scoring method varies, but which one is most suitable for predicting the prognosis still unclear. We aimed to evaluate the diagnostic performance of Automated (Auto)-, noncontrast CT (NCCT)- and CT per...

    Authors: Tiegong Wang, Luguang Chen, Xianglan Jin, Yuan Yuan, Qianwen Zhang, Chengwei Shao and Jianping Lu
    Citation: BMC Medical Imaging 2021 21:67
  20. Reidentification of prior nodules for temporal comparison is an important but time-consuming step in lung cancer screening. We develop and evaluate an automated nodule detector that utilizes the axial-slice nu...

    Authors: Yeshwant Reddy Chillakuru, Kyle Kranen, Vishnu Doppalapudi, Zhangyuan Xiong, Letian Fu, Aarash Heydari, Aditya Sheth, Youngho Seo, Thienkhai Vu and Jae Ho Sohn
    Citation: BMC Medical Imaging 2021 21:66
  21. Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease, characterized by bile duct inflammation and destruction, leading to biliary fibrosis and cirrhosis. The purpose of this study was to...

    Authors: Narine Mesropyan, Patrick Kupczyk, Guido M. Kukuk, Leona Dold, Tobias Weismueller, Christoph Endler, Alexander Isaak, Anton Faron, Alois M. Sprinkart, Claus C. Pieper, Daniel Kuetting, Christian P. Strassburg, Ulrike I. Attenberger and Julian A. Luetkens
    Citation: BMC Medical Imaging 2021 21:65
  22. Four-dimensional computed tomography (4DCT) is a commonly performed examination in the management of primary hyperparathyroidism, combining three-dimensional imaging with enhancement over time as the fourth di...

    Authors: Steven Raeymaeckers, Yannick De Brucker, Tim Vanderhasselt, Nico Buls and Johan De Mey
    Citation: BMC Medical Imaging 2021 21:64
  23. Chronic allograft injury (CAI) is a significant reason for which many grafts were lost. The study was conducted to assess the usefulness of diffusional kurtosis imaging (DKI) technology in the non-invasive ass...

    Authors: Xin Zheng, Min Li, Pan Wang, Xiangnan Li, Qiang Zhang, Song Zeng, Tao Jiang and Xiaopeng Hu
    Citation: BMC Medical Imaging 2021 21:63
  24. Intravenous thrombolysis (IVT) is a rapid and effective treatment in the early stage of ischemic stroke patients and the purpose of this work is to explore the significance of Hounsfield unit (HU) value in Alb...

    Authors: Zhengqi Zhu, Ru Zhang, Kaixuan Ren, Ruochen Cong, Xiangyang Zhu, Li Zhu and Tianle Wang
    Citation: BMC Medical Imaging 2021 21:62
  25. This study attempted to compare the radiopharmaceutical uptake findings of planar bone scintigraphy (BS) and single photon emission computed tomography (SPECT)/computed tomography (CT) performed on knee joints.

    Authors: Young-Sil An, Do Young Park, Byoung-Hyun Min, Su Jin Lee and Joon-Kee Yoon
    Citation: BMC Medical Imaging 2021 21:60
  26. This study aimed to develope and validate a radiomics nomogram by integrating the quantitative radiomics characteristics of No.3 lymph nodes (LNs) and primary tumors to better predict preoperative lymph node m...

    Authors: Xiaoxiao Wang, Cong Li, Mengjie Fang, Liwen Zhang, Lianzhen Zhong, Di Dong, Jie Tian and Xiuhong Shan
    Citation: BMC Medical Imaging 2021 21:58
  27. Spatial and temporal lung infection distributions of coronavirus disease 2019 (COVID-19) and their changes could reveal important patterns to better understand the disease and its time course. This paper prese...

    Authors: Dongdong Gu, Liyun Chen, Fei Shan, Liming Xia, Jun Liu, Zhanhao Mo, Fuhua Yan, Bin Song, Yaozong Gao, Xiaohuan Cao, Yanbo Chen, Ying Shao, Miaofei Han, Bin Wang, Guocai Liu, Qian Wang…
    Citation: BMC Medical Imaging 2021 21:57
  28. Giant cell arteritis (GCA) is the most common form of systemic vasculitis in persons aged 50 years and older. Medium and large vessels, like the temporal and axillary arteries, are commonly affected. Typical s...

    Authors: Lara Clarissa Burg, Wolfgang Andreas Schmidt, Peter Brossart, Katharina Isabell Reinking, Franziskus Maria Schützeichel, Robert Patrick Finger and Valentin Sebastian Schäfer
    Citation: BMC Medical Imaging 2021 21:55
  29. Distinguishing parotid pleomorphic adenoma (PPA) from parotid adenolymphoma (PA) is important for precision treatment, but there is a lack of readily available diagnostic methods. In this study, we aimed to ex...

    Authors: Le-le Song, Shun-jun Chen, Wang Chen, Zhan Shi, Xiao-dong Wang, Li-na Song and Dian-sen Chen
    Citation: BMC Medical Imaging 2021 21:54
  30. Adult-attention-deficit-hyperactive-disorder (ADHD) is often unrecognized condition. FMRI examination along with neuropsychological testing might strengthen the diagnosis. We hypothesized that ADHD-adults with...

    Authors: Jatta Berberat, Ruth Huggenberger, Margherita Montali, Philipp Gruber, Achmed Pircher, Karl-Olof Lövblad, Hanspeter E. Killer and Luca Remonda
    Citation: BMC Medical Imaging 2021 21:53
  31. The visualization of the tibial nerve and its branches in the ankle canal is helpful for the diagnosis of local lesions and compression, and it is also useful for clinical observation and surgical planning. Th...

    Authors: Yan Zhang, Xucheng He, Juan Li, Ju Ye, Wenjuan Han, Shanshan Zhou, Jianzhong Zhu, Guisheng Wang and Xiaoxia Chen
    Citation: BMC Medical Imaging 2021 21:51
  32. This study is aimed to explore the factors influencing the visualization of the anterior peritoneal reflection (APR) and evaluated the feasibility of measuring the distance from the anal verge to APR (AV-APR),...

    Authors: Shaoting Zhang, Fangying Chen, Xiaolu Ma, Minjie Wang, Guanyu Yu, Fu Shen, Xianhua Gao and Jianping Lu
    Citation: BMC Medical Imaging 2021 21:50
  33. Staging of non-small-cell lung cancer (NSCLC) is a multidisciplinary process involving imaging, endoscopic and surgical techniques. This study aims at investigating the diagnostic accuracy of 18F-FDG PET/CT, CT s...

    Authors: Akram Al-Ibraheem, Nader Hirmas, Stefano Fanti, Diana Paez, Fawzi Abuhijla, Dalia Al-Rimawi, Ula Al-Rasheed, Riad Abdeljalil, Feras Hawari, Kamal Alrabi and Asem Mansour
    Citation: BMC Medical Imaging 2021 21:49
  34. Non-mass enhancement (NME) is a diagnostic dilemma and highly reliant on the experience of the radiologists. Texture analysis (TA) could serve as an objective method to quantify lesion characteristics. However...

    Authors: Yu Tan, Hui Mai, Zhiqing Huang, Li Zhang, Chengwei Li, Songxin Wu, Huang Huang, Wen Tang, Yongxi Liu and Kuiming Jiang
    Citation: BMC Medical Imaging 2021 21:48
  35. Radiofrequency ablation (RFA) is recommended for the treatment of benign thyroid nodules. However, data on the clinical role of RFA for benign thyroid nodules in patients with history of thyroid lobectomy are ...

    Authors: Lin Yan, Mingbo Zhang, Fang Xie, Jun Ma, Jing Xiao and Yukun Luo
    Citation: BMC Medical Imaging 2021 21:47
  36. This study aimed to compare panoramic radiography (PAN) and cone beam computed tomography (CBCT) determinations of implant-to-root dimensions (IRD) in anterior and posterior maxillary regions, and to help dete...

    Authors: Annika Bertram, Alexander W. Eckert and Rüdiger Emshoff
    Citation: BMC Medical Imaging 2021 21:46
  37. To investigate left atrial shape differences on CT scans of atrial fibrillation (AF) patients with (AF+) versus without (AF−) post-ablation recurrence and whether these shape differences predict AF recurrence.

    Authors: Thomas Atta-Fosu, Michael LaBarbera, Soumya Ghose, Paul Schoenhagen, Walid Saliba, Patrick J. Tchou, Bruce D. Lindsay, Milind Y. Desai, Deborah Kwon, Mina K. Chung and Anant Madabhushi
    Citation: BMC Medical Imaging 2021 21:45
  38. Chest radiograph (CXR) prescribing pattern and practice vary widely among pediatric intensive care units (PICU). ‘On demand’ approach is increasingly recommended as against daily ‘routine’ CXRs; however, the r...

    Authors: Rajeev Gupta, Karthi Nallasamy, Vijai Williams, Akshay Kumar Saxena and Muralidharan Jayashree
    Citation: BMC Medical Imaging 2021 21:44
  39. The purpose of this study was to investigate the relationship between breast density, age, and mammographic lesion type among Chinese breast cancer patients included in a large clinical dataset.

    Authors: Yu Ji, Boxin Li, Rui Zhao, Ying Zhang, Junjun Liu and Hong Lu
    Citation: BMC Medical Imaging 2021 21:43
  40. Collecting (Bellini) duct carcinoma (CDC) is a highly malignant and rare kidney tumor. We report our 12-year experience with CDC and the results of a retrospective analysis of patients and tumor characteristic...

    Authors: Zhehao Lyu, Lili Liu, Huimin Li, Haibo Wang, Qi Liu, Tingting Chen, Meiling Xu, Lin Tian and Peng Fu
    Citation: BMC Medical Imaging 2021 21:42
  41. Assessment of tibiofibular reduction presents an intra- and postoperative challenge. Numerous two-dimensional measurement methods have been described, most of them highly dependent on leg orientation and rater...

    Authors: Firas Souleiman, Martin Heilemann, Robert Hennings, Mareike Hennings, Alexis Klengel, Pierre Hepp, Georg Osterhoff and Annette B. Ahrberg
    Citation: BMC Medical Imaging 2021 21:41
  42. The objective of this study was to analyze the accuracy of gadolinium–ethoxybenzyl–diethylenetriamine penta–acetic acid enhanced magnetic resonance imaging (Gd–EOB–DTPA–MRI) for predicting microvascular invasi...

    Authors: Meng Zhou, Dan Shan, Chunhui Zhang, Jianhua Nie, Guangyu Wang, Yanqiao Zhang, Yang Zhou and Tongsen Zheng
    Citation: BMC Medical Imaging 2021 21:40
  43. Quantitative bone SPECT/CT is useful for disease follow up and inter-patient comparison. For bone metastatic malignant lesions, spine is the most commonly invaded site. However, Quantitative studies with large...

    Authors: Na Qi, Qingyuan Meng, Zhiwen You, Huiqian Chen, Yi Shou and Jun Zhao
    Citation: BMC Medical Imaging 2021 21:39

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