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  1. Osteoporosis is defined as a skeletal disorder characterized by compromised bone strength due to a reduction of bone mass and deterioration of bone microstructure predisposing an individual to an increased ris...

    Authors: Thomas Baum, Eduardo Grande Garcia, Rainer Burgkart, Olga Gordijenko, Hans Liebl, Pia M. Jungmann, Michael Gruber, Tina Zahel, Ernst J. Rummeny, Simone Waldt and Jan S. Bauer
    Citation: BMC Medical Imaging 2015 15:22
  2. Recent advances in bronchoscopy, such as transbronchial biopsy (TBB) using endobronchial ultrasonography with a guide sheath (EBUS-GS), have improved the diagnostic yield of small-sized peripheral lung lesions...

    Authors: Tomoyuki Minezawa, Takuya Okamura, Hiroshi Yatsuya, Naoki Yamamoto, Sayako Morikawa, Teppei Yamaguchi, Mariko Morishita, Yoshikazu Niwa, Tomoko Takeyama, Yuki Mieno, Tami Hoshino, Sakurako Uozu, Yasuhiro Goto, Masamichi Hayashi, Sumito Isogai, Masaki Matsuo…
    Citation: BMC Medical Imaging 2015 15:21
  3. Respiratory gating is often used in 4D-flow acquisition to reduce motion artifacts. However, gating increases scan time. The aim of this study was to investigate if respiratory gating can be excluded from 4D f...

    Authors: Mikael Kanski, Johannes Töger, Katarina Steding-Ehrenborg, Christos Xanthis, Karin Markenroth Bloch, Einar Heiberg, Marcus Carlsson and Håkan Arheden
    Citation: BMC Medical Imaging 2015 15:20
  4. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a promising technique to characterize pathology and evaluate treatment response. However, analysis of DCE-MRI data is complex and benefits from...

    Authors: Samuel R. Barnes, Thomas S. C. Ng, Naomi Santa-Maria, Axel Montagne, Berislav V. Zlokovic and Russell E. Jacobs
    Citation: BMC Medical Imaging 2015 15:19
  5. The diagnosis of hip pain after total hip replacement (THR) represents a highly challenging question that is of increasing concern to orthopedic surgeons. This retrospective study assesses bone scintigraphy wi...

    Authors: Oliver Dobrindt, Holger Amthauer, Alexander Krueger, Juri Ruf, Heiko Wissel, Oliver S Grosser, Max Seidensticker and Christoph H Lohmann
    Citation: BMC Medical Imaging 2015 15:18
  6. In children, septic arthritis (SA) of the hip is either primary or concomitant with acute haematogenous osteomyelitis (AHO). However, seldom, patients with isolated SA at presentation, may later show osteomyel...

    Authors: Laura Merlini, Mehrak Anooshiravani and Dimitri Ceroni
    Citation: BMC Medical Imaging 2015 15:17
  7. Alveolar macrophages, with their high functional plasticity, were reported to orchestrate the induction and resolution of inflammatory processes in chronic pulmonary diseases. Noninvasive imaging modalities th...

    Authors: Achraf Al Faraj, Asma Sultana Shaik and Mohammed Alnafea
    Citation: BMC Medical Imaging 2015 15:16
  8. Hepatocellular carcinoma (HCC) remains a global health problem with unique diagnostic and therapeutic challenges, including difficulties in identifying the highest risk patients. Previous work from our lab has...

    Authors: Paul R. Territo, Mary Maluccio, Amanda A. Riley, Brian P. McCarthy, James Fletcher, Mark Tann, Romil Saxena and Nicholas J. Skill
    Citation: BMC Medical Imaging 2015 15:15
  9. Pancreatic cancer accompanied by a moderate-sized pseudocyst with extrapancreatic growth is extremely rare. Diagnosis of pancreatic cancer on preoperative imaging is difficult when the pancreatic parenchyma is...

    Authors: Yu Ohkura, Kazunari Sasaki, Masamichi Matsuda, Masaji Hashimoto, Takeshi Fujii and Goro Watanabe
    Citation: BMC Medical Imaging 2015 15:14
  10. Manual and semi-automatic analyses of images, acquired in vivo by confocal microscopy, are often used to determine the quality of corneal endothelium in the human eye. These procedures are highly time consumin...

    Authors: Bettina Selig, Koenraad A Vermeer, Bernd Rieger, Toine Hillenaar and Cris L Luengo Hendriks
    Citation: BMC Medical Imaging 2015 15:13
  11. Patients with facial cancers can experience disfigurement as they may undergo considerable appearance changes from their illness and its treatment. Individuals with difficulties adjusting to facial cancer are ...

    Authors: Juhun Lee, Michelle C Fingeret, Alan C Bovik, Gregory P Reece, Roman J Skoracki, Matthew M Hanasono and Mia K Markey
    Citation: BMC Medical Imaging 2015 15:12
  12. The introduction of a standardized SPECT/CT algorithm including a localization scheme, which allows accurate identification of specific patterns and thresholds of SPECT/CT tracer uptake, could lead to a better...

    Authors: Basil Suter, Enrique Testa, Patrick Stämpfli, Praveen Konala, Helmut Rasch, Niklaus F Friederich and Michael T Hirschmann
    Citation: BMC Medical Imaging 2015 15:11
  13. Positron emission tomography scanners collect measurements of a patient’s in vivo radiotracer distribution. The system detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), ...

    Authors: Alexander Wong, Chenyi Liu, Xiao Yu Wang, Paul Fieguth and Hongxia Bie
    Citation: BMC Medical Imaging 2015 15:10
  14. Speech recognition (SR) technology, the process whereby spoken words are converted to digital text, has been used in radiology reporting since 1981. It was initially anticipated that SR would dominate radiolog...

    Authors: Jacqueline du Toit, Retha Hattingh and Richard Pitcher
    Citation: BMC Medical Imaging 2015 15:8
  15. The objective of this study was to evaluate the feasibility and diagnostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and 99mTc-methylenediphosphonate (MDP) ...

    Authors: Lin Zhang, Lihua Chen, Qiao Xie, Yongke Zhang, Lin Cheng, Haitao Li and Jian Wang
    Citation: BMC Medical Imaging 2015 15:7
  16. Independent central reading or off-site reading of imaging endpoints is increasingly used in clinical trials. Clinician-reported outcomes, such as endoscopic disease activity scores, have been shown to be subj...

    Authors: Klaus Gottlieb and Fez Hussain
    Citation: BMC Medical Imaging 2015 15:6
  17. Manual segmentations of the whole intracranial vault in high-resolution magnetic resonance images are often regarded as very time-consuming. Therefore it is common to only segment a few linearly spaced intracr...

    Authors: Niklas Klasson, Erik Olsson, Mats Rudemo, Carl Eckerström, Helge Malmgren and Anders Wallin
    Citation: BMC Medical Imaging 2015 15:5
  18. Hibernomas are rare benign soft-tissue tumours arising from brown fat tissue. Although imaging characteristics are not specific certain imaging features, common locations and patient demographics may suggest h...

    Authors: Dirk Daubner, Stephanie Spieth, Jessica Pablik, Klaus Zöphel, Tobias Paulus and Michael Laniado
    Citation: BMC Medical Imaging 2015 15:4
  19. The main objective of the present method was to automatically obtain a spatial curve of the thoracic and lumbar spine based on a 3D shape measurement of a human torso with developed scoliosis. Manual determina...

    Authors: Primož Poredoš, Dušan Čelan, Janez Možina and Matija Jezeršek
    Citation: BMC Medical Imaging 2015 15:2
  20. Vibro-acoustography (VA) is a newly developed imaging technology that is based on low-frequency vibrations induced in the object by the radiation force of ultrasound. VA is sensitive to the dynamic characteris...

    Authors: Azra Alizad, Mohammad Mehrmohammadi, Karthik Ghosh, Katrina N Glazebrook, Rickey E Carter, Leman Gunbery Karaberkmez, Dana H Whaley and Mostafa Fatemi
    Citation: BMC Medical Imaging 2014 14:40
  21. Penile paraffinoma is a well-known delayed complication of paraffin oil injection into the penis for penile girth augmentation but its MRI features have not been previously described.

    Authors: Luigi Cormio, Giuseppe Di Fino, Carmen Scavone, Oscar Selvaggio, Paolo Massenio, Francesca Sanguedolce, Luca Macarini and Giuseppe Carrieri
    Citation: BMC Medical Imaging 2014 14:39
  22. The correct segmentation of myofibres in histological muscle biopsy images is a critical step in the automatic analysis process. Errors occurring as a result of incorrect segmentations have a compounding effec...

    Authors: Harry Strange, Ian Scott and Reyer Zwiggelaar
    Citation: BMC Medical Imaging 2014 14:38
  23. Optical coherence tomography (OCT) is a minimally invasive imaging technique, which utilizes the spatial and temporal coherence properties of optical waves backscattered from biological material. Recent advanc...

    Authors: Chenyi Liu, Alexander Wong, Paul Fieguth, Kostadinka Bizheva and Hongxia Bie
    Citation: BMC Medical Imaging 2014 14:37
  24. Early and accurate diagnosis of melanoma, the deadliest type of skin cancer, has the potential to reduce morbidity and mortality rate. However, early diagnosis of melanoma is not trivial even for experienced d...

    Authors: Lin Li, Qizhi Zhang, Yihua Ding, Huabei Jiang, Bruce H Thiers and James Z Wang
    Citation: BMC Medical Imaging 2014 14:36
  25. Manual annotation of landmarks is a known source of variance, which exist in all fields of medical imaging, influencing the accuracy and interpretation of the results. However, the variability of human facial ...

    Authors: Jens Fagertun, Stine Harder, Anders Rosengren, Christian Moeller, Thomas Werge, Rasmus R Paulsen and Thomas F Hansen
    Citation: BMC Medical Imaging 2014 14:35
  26. Adverse reactions to iodinated and gadolinium contrast media are an important clinical issue. Although some guidelines have proposed oral steroid premedication protocols to prevent adverse reactions, some pati...

    Authors: Akiko Jingu, Junya Fukuda, Ayako Taketomi-Takahashi and Yoshito Tsushima
    Citation: BMC Medical Imaging 2014 14:34
  27. Two-dimensional projection radiographs have been traditionally considered the modality of choice for cephalometric analysis. To overcome the shortcomings of two-dimensional images, three-dimensional computed t...

    Authors: Shoaleh Shahidi, Ehsan Bahrampour, Elham Soltanimehr, Ali Zamani, Morteza Oshagh, Marzieh Moattari and Alireza Mehdizadeh
    Citation: BMC Medical Imaging 2014 14:32
  28. Transcatheter aortic valve implantation involves percutaneously implanting a biomechanical aortic valve to treat severe aortic stenosis. In order to select a proper device, precise sizing of the aortic valve a...

    Authors: Jørn Bersvendsen, Jan O Beitnes, Stig Urheim, Svend Aakhus and Eigil Samset
    Citation: BMC Medical Imaging 2014 14:31
  29. To investigate the impact of high pitch cardiac CT vs. retrospective ECG gated CT on the quantification of calcified vessel stenoses, with assessment of the influence of tube voltage, reconstruction kernel and...

    Authors: Tobias Penzkofer, Eva Donandt, Peter Isfort, Thomas Allmendinger, Christiane K Kuhl, Andreas H Mahnken and Philipp Bruners
    Citation: BMC Medical Imaging 2014 14:30
  30. In total knee arthroplasty (TKA), cement penetration between 3 and 5 mm beneath the tibial tray is required to prevent loosening of the tibia component. The objective of this study was to develop and validate ...

    Authors: Hennie Verburg, Laurens C van de Ridder, Vincent WJ Verhoeven and Peter Pilot
    Citation: BMC Medical Imaging 2014 14:29
  31. CT perfusion images have a high contrast ratio between voxels representing different anatomy, such as tissue or vessels, which makes image segmentation of tissue and vascular regions relatively easy. However, ...

    Authors: David S Wack, Kenneth V Snyder, Kevin F Seals and Adnan H Siddiqui
    Citation: BMC Medical Imaging 2014 14:28
  32. Thermal ablation of colorectal liver metastases (CRLM) may result in local progression, which generally appear within a year of treatment. As the timely diagnosis of this progression allows potentially curativ...

    Authors: Karin Nielsen, Hester J Scheffer, Indra C Pieters, Aukje AJM van Tilborg, Jan-Hein TM van Waesberghe, Daniela E Oprea-Lager, Martijn R Meijerink, Geert Kazemier, Otto S Hoekstra, Hermien WH Schreurs, Colin Sietses, Sybren Meijer, Emile FI Comans and Petrousjka MP van den Tol
    Citation: BMC Medical Imaging 2014 14:27
  33. Diffusion-weighted MRI (DWI) has been used in neurosurgical practice mainly to distinguish cerebral metastases from abscess and glioma. There is evidence from other solid organ cancers and metastases that DWI ...

    Authors: Rasheed Zakaria, Kumar Das, Mark Radon, Maneesh Bhojak, Philip R Rudland, Vanessa Sluming and Michael D Jenkinson
    Citation: BMC Medical Imaging 2014 14:26
  34. Determination of regional lung air volume has several clinical applications. This study investigates the use of mid-tidal breathing CT scans to provide regional lung volume data.

    Authors: John Fleming, Joy Conway, Caroline Majoral, Michael Bennett, Georges Caillibotte, Spyridon Montesantos and Ira Katz
    Citation: BMC Medical Imaging 2014 14:25
  35. A bone scan is a common method for monitoring bone metastases in patients with advanced prostate cancer. The Bone Scan Index (BSI) measures the tumor burden on the skeleton, expressed as a percentage of the to...

    Authors: Jonas Kalderstam, May Sadik, Lars Edenbrandt and Mattias Ohlsson
    Citation: BMC Medical Imaging 2014 14:24
  36. Endobronchial ultrasonography (EBUS) has been applied as a routine procedure for the diagnostic of hiliar and mediastinal nodes. The authors assessed the relationship between the echographic appearance of medi...

    Authors: José Antonio Fiz, Enrique Monte-Moreno, Felipe Andreo, Santiago José Auteri, José Sanz-Santos, Pere Serra, Gloria Bonet, Eva Castellà and Juan Ruiz Manzano
    Citation: BMC Medical Imaging 2014 14:22
  37. Alzheimer’s disease (AD) is a progressive, incurable neurodegenerative disease and the most common type of dementia. It cannot be prevented, cured or drastically slowed, even though AD research has increased i...

    Authors: Lene Lillemark, Lauge Sørensen, Akshay Pai, Erik B Dam and Mads Nielsen
    Citation: BMC Medical Imaging 2014 14:21
  38. Studies of prenatal detection of congenital heart disease (CHD) in the UK, Italy, and Norway indicate that it should be possible to improve the prenatal detection rate of CHD in Sweden. These studies have show...

    Authors: Eric Hildebrand, Madeleine Abrandt Dahlgren, Catarina Sved, Tomas Gottvall, Marie Blomberg and Birgitta Janerot-Sjoberg
    Citation: BMC Medical Imaging 2014 14:20
  39. FDG-PET/CT is part of the standard diagnostic management of a patients with a large variety of common and less common malignant tumors, based on the increased glucose metabolism within tumors.

    Authors: Patrick Schöffski, Christophe M Deroose, Olivier Gheysens, Nele Lips, Koen Slabbaert, Ben Vancleynenbreugel, Philippe Moerman and Willy E Peetermans
    Citation: BMC Medical Imaging 2014 14:19
  40. Ensuring an adequate blood supply is essential to the safe performance of an anastomosis during esophagectomy and the prevention of anastomotic leakage. Recently, indocyanine green (ICG) fluorescence imaging h...

    Authors: Yasushi Rino, Norio Yukawa, Tsutomu Sato, Naoto Yamamoto, Hiroshi Tamagawa, Shinichi Hasegawa, Takashi Oshima, Takaki Yoshikawa, Munetaka Masuda and Toshio Imada
    Citation: BMC Medical Imaging 2014 14:18
  41. Hepatic angiomyolipoma is a rare benign mesenchymal tumor. We report an unusual case of a patient with multiple hepatic angiomyolipomas exhibiting high 18 F-fluorodeoxyglucose (FDG) uptake.

    Authors: Soma Kumasaka, Yukiko Arisaka, Azusa Tokue, Tetsuya Higuchi, Takahito Nakajima and Yoshito Tsushima
    Citation: BMC Medical Imaging 2014 14:17
  42. Magnetic resonance cholangiopancreatography (MRCP) is an established technique for the evaluation of intra- and extrahepatic bile ducts in patients with known or suspected hepatobiliary disease. However, the i...

    Authors: Kristina Imeen Ringe, Dagmar Hartung, Christian von Falck, Frank Wacker and Hans-Jürgen Raatschen
    Citation: BMC Medical Imaging 2014 14:16
  43. We tested the feasibility of a simple method for assessment of prostate cancer (PCa) aggressiveness using diffusion-weighted magnetic resonance imaging (MRI) to calculate apparent diffusion coefficient (ADC) r...

    Authors: Andrei Lebovici, Silviu A Sfrangeu, Diana Feier, Cosmin Caraiani, Ciprian Lucan, Mihai Suciu, Florin Elec, Gheorghita Iacob and Mircea Buruian
    Citation: BMC Medical Imaging 2014 14:15
  44. Since analysis of Sidestream Dark Field images still requires subjective interpretation, we wanted to determine intra-observer repeatability and to estimate the correlation between different evaluation methods.

    Authors: Sandra M Petersen, Gorm Greisen, Simon Hyttel-Sorensen and Gitte H Hahn
    Citation: BMC Medical Imaging 2014 14:14

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