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  1. Hepatic angiomyolipoma is a rare benign mesenchymal tumor. We report an unusual case of a patient with multiple hepatic angiomyolipomas exhibiting high 18 F-fluorodeoxyglucose (FDG) uptake.

    Authors: Soma Kumasaka, Yukiko Arisaka, Azusa Tokue, Tetsuya Higuchi, Takahito Nakajima and Yoshito Tsushima
    Citation: BMC Medical Imaging 2014 14:17
  2. Magnetic resonance cholangiopancreatography (MRCP) is an established technique for the evaluation of intra- and extrahepatic bile ducts in patients with known or suspected hepatobiliary disease. However, the i...

    Authors: Kristina Imeen Ringe, Dagmar Hartung, Christian von Falck, Frank Wacker and Hans-Jürgen Raatschen
    Citation: BMC Medical Imaging 2014 14:16
  3. We tested the feasibility of a simple method for assessment of prostate cancer (PCa) aggressiveness using diffusion-weighted magnetic resonance imaging (MRI) to calculate apparent diffusion coefficient (ADC) r...

    Authors: Andrei Lebovici, Silviu A Sfrangeu, Diana Feier, Cosmin Caraiani, Ciprian Lucan, Mihai Suciu, Florin Elec, Gheorghita Iacob and Mircea Buruian
    Citation: BMC Medical Imaging 2014 14:15
  4. Since analysis of Sidestream Dark Field images still requires subjective interpretation, we wanted to determine intra-observer repeatability and to estimate the correlation between different evaluation methods.

    Authors: Sandra M Petersen, Gorm Greisen, Simon Hyttel-Sorensen and Gitte H Hahn
    Citation: BMC Medical Imaging 2014 14:14
  5. Objective physical assessment of patients with lumbar spondylosis involves plain film radiographs (PFR) viewing and interpretation by the radiologists. Physiotherapists also routinely assess PFR within the sco...

    Authors: Ajediran I Bello, Eric K Ofori, Oluwasegun J Alabi and David N Adjei
    Citation: BMC Medical Imaging 2014 14:13
  6. Use of ultrasound in brain tumor surgery is common. The difference in attenuation between brain and isotonic saline may cause artifacts that degrade the ultrasound images, potentially affecting resection grade...

    Authors: Asgeir S Jakola, Arve Jørgensen, Tormod Selbekk, Ralf-Peter Michler, Ole Solheim, Sverre H Torp, Lisa M Sagberg, Petter Aadahl and Geirmund Unsgård
    Citation: BMC Medical Imaging 2014 14:11
  7. Ultrasound is considered a reliable, widely available, non-invasive and inexpensive imaging technique for assessing soft tissue involvement in Lateral epicondylalgia. Despite the number of diagnostic studies f...

    Authors: Valentin C Dones III, Karen Grimmer, Kerry Thoirs, Consuelo G Suarez and Julie Luker
    Citation: BMC Medical Imaging 2014 14:10
  8. Coccidioidomycosis is an endemic fungal infection in the southwestern of United States. Most infections are asymptomatic or manifest with mild respiratory complaints. Rare cases may cause extrapulmonary or dis...

    Authors: Yi-Chen Li, George Calvert, Christopher J Hanrahan, Kevin B Jones and Robert Lor Randall
    Citation: BMC Medical Imaging 2014 14:8
  9. Digital image analysis has the potential to address issues surrounding traditional histological techniques including a lack of objectivity and high variability, through the application of quantitative analysis...

    Authors: Juliana M Haggerty, Xiao N Wang, Anne Dickinson, Chris J O’Malley and Elaine B Martin
    Citation: BMC Medical Imaging 2014 14:7
  10. The European Society of Cardiology recommends that patients with >10% area of ischemia should receive revascularization. We investigated inter-observer variability for the extent of ischemic defects reported b...

    Authors: Lars Edenbrandt, Peter Höglund, Sophia Frantz, Philip Hasbak, Allan Johansen, Lena Johansson, Annett Kammeier, Oliver Lindner, Milan Lomsky, Shinro Matsuo, Kenichi Nakajima, Karin Nyström, Eva Olsson, Karl Sjöstrand, Sven-Eric Svensson, Hiroshi Wakabayashi…
    Citation: BMC Medical Imaging 2014 14:5
  11. Delineation of the target volume is a time-consuming task in radiotherapy treatment planning, yet essential for a successful treatment of cancers such as prostate cancer. To facilitate the delineation procedur...

    Authors: Jörn Schulz, Stein Olav Skrøvseth, Veronika Kristine Tømmerås, Kirsten Marienhagen and Fred Godtliebsen
    Citation: BMC Medical Imaging 2014 14:4
  12. The Editors of BMC Medical Imaging would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013)

    Authors: Fernando Marques
    Citation: BMC Medical Imaging 2014 14:3
  13. Size and shape of the treatment zone after Irreversible electroporation (IRE) can be difficult to depict due to the use of multiple applicators with complex spatial configuration. Exact geometrical definition ...

    Authors: Dominik Vollherbst, Stefan Fritz, Sascha Zelzer, Miguel F Wachter, Maya B Wolf, Ulrike Stampfl, Daniel Gnutzmann, Nadine Bellemann, Anne Schmitz, Jürgen Knapp, Philippe L Pereira, Hans U Kauczor, Jens Werner, Boris A Radeleff and Christof M Sommer
    Citation: BMC Medical Imaging 2014 14:2
  14. Assessing heterogeneity in lung images can be an important diagnosis tool. We present a novel and objective method for assessing lung damage in a rat model of emphysema. We combined a three-dimensional (3D) co...

    Authors: Richard E Jacob and James P Carson
    Citation: BMC Medical Imaging 2014 14:1
  15. To evaluate the inter-study, inter-reader and intra-reader reproducibility of cardiac cine and scar imaging in rats using a clinical 3.0 Tesla magnetic resonance (MR) system.

    Authors: Robert Manka, Cosima Jahnke, Thomas Hucko, Thore Dietrich, Rolf Gebker, Bernhard Schnackenburg, Kristof Graf and Ingo Paetsch
    Citation: BMC Medical Imaging 2013 13:44
  16. Diagnostic performance in breast screening programs may be influenced by the prior probability of disease. Since breast cancer incidence is roughly half a percent in the general population there is a large pro...

    Authors: Edward J Kendall, Michael G Barnett and Krista Chytyk-Praznik
    Citation: BMC Medical Imaging 2013 13:43
  17. Sentinel node biopsy often results in the identification and removal of multiple nodes as sentinel nodes, although most of these nodes could be non-sentinel nodes. This study investigated whether computed tomo...

    Authors: Kazuyoshi Motomura, Hiroshi Sumino, Atsushi Noguchi, Takashi Horinouchi and Katsuyuki Nakanishi
    Citation: BMC Medical Imaging 2013 13:42
  18. Correct characterization of focal solid hepatic lesions has always been a challenge and is of great diagnostic and therapeutic relevance. The purpose of this study was to determine the added value of hepatobil...

    Authors: Michael Haimerl, Max Wächtler, Ivan Platzek, Rene Müller-Wille, Christoph Niessen, Patrick Hoffstetter, Andreas Georg Schreyer, Christian Stroszczynski and Philipp Wiggermann
    Citation: BMC Medical Imaging 2013 13:41
  19. Concerns have been raised regarding growth in advanced diagnostic imaging use. This study evaluated trends in national outpatient MRI/CT utilization rates during 2000-2009 and factors associated with utilization.

    Authors: Kathleen Lang, Huan Huang, David W Lee, Victoria Federico and Joseph Menzin
    Citation: BMC Medical Imaging 2013 13:40
  20. No study relating the changes obtained in the architecture of erector spinae (ES) muscle were registered with ultrasound and different intensities of muscle contraction recorded by surface EMG (electromyograph...

    Authors: Antonio I Cuesta-Vargas and Manuel Gonzalez-Sanchez
    Citation: BMC Medical Imaging 2013 13:38
  21. Psoas abscess complicating tuberculous spondylitis is a rare morbidity in extrapulmonary tuberculosis. There are no established guidelines for evaluating the clinical response of psoas abscess. Although severa...

    Authors: Yoshifumi Kimizuka, Makoto Ishii, Koji Murakami, Kota Ishioka, Kazuma Yagi, Ken Ishii, Kota Watanabe, Kenzo Soejima, Tomoko Betsuyaku and Naoki Hasegawa
    Citation: BMC Medical Imaging 2013 13:37
  22. Automated whole breast ultrasound scanners of the latest generation have reached a level of comfortable application and high quality volume acquisition. Nevertheless, there is a lack of data concerning this te...

    Authors: Sebastian Wojcinski, Samuel Gyapong, André Farrokh, Philipp Soergel, Peter Hillemanns and Friedrich Degenhardt
    Citation: BMC Medical Imaging 2013 13:36
  23. Non-invasive imaging of the biodistribution of novel therapeutics including gene therapy vectors in animal models is essential.

    Authors: Nicola Ingram, Stuart A Macnab, Gemma Marston, Nigel Scott, Ian M Carr, Alexander F Markham, Adrian Whitehouse and P Louise Coletta
    Citation: BMC Medical Imaging 2013 13:35
  24. Correct sagittal alignment with a balanced pelvis and spine is crucial in the management of spinal disorders. The pelvic incidence (PI) describes the sagittal pelvic alignment and is position-independent. It h...

    Authors: Thorsten Jentzsch, James Geiger, Samy Bouaicha, Ksenija Slankamenac, Thi Dan Linh Nguyen-Kim and Clément ML Werner
    Citation: BMC Medical Imaging 2013 13:34
  25. Magnetic resonance imaging (MRI) guided wire localization presents several challenges apart from the technical difficulties. An alternative to this conventional localization method using a wire is the radio-gu...

    Authors: Fernanda Philadelpho Arantes Pereira, Gabriela Martins, Maria Julia Gregorio Calas, Maria Veronica Fonseca Torres de Oliveira, Emerson Leandro Gasparetto and Lea Mirian Barbosa da Fonseca
    Citation: BMC Medical Imaging 2013 13:33
  26. We previously demonstrated that superparamagnetic iron oxide (SPIO)-enhanced MR imaging is promising for the detection of metastases in sentinel nodes localized by CT-lymphography in patients with breast cance...

    Authors: Kazuyoshi Motomura, Tetsuta Izumi, Souichirou Tateishi, Hiroshi Sumino, Atsushi Noguchi, Takashi Horinouchi and Katsuyuki Nakanishi
    Citation: BMC Medical Imaging 2013 13:32
  27. To evaluate whether Contrast Enhanced Ultrasund (CEUS) with microbubbles (MBs) targeted to VEGFR-2 is able to characterize in vivo the VEGFR-2 expression in the tumor vasculature of a mouse model of thyroid cance...

    Authors: Marcello Mancini, Adelaide Greco, Giuliana Salvatore, Raffaele Liuzzi, Gennaro Di Maro, Emilia Vergara, Gennaro Chiappetta, Rosa Pasquinelli, Arturo Brunetti and Marco Salvatore
    Citation: BMC Medical Imaging 2013 13:31
  28. Previous data using T1-weighted MRI demonstrated neck muscle fat infiltration (MFI) in patients with poor functional recovery following whiplash. Such findings do not occur in those with milder symptoms of whi...

    Authors: James M Elliott, David M Walton, Alfred Rademaker and Todd B Parrish
    Citation: BMC Medical Imaging 2013 13:30
  29. Activity of disease in patients with multiple sclerosis (MS) is monitored by detecting and delineating hyper-intense lesions on MRI scans. The Minimum Area Contour Change (MACC) algorithm has been created with...

    Authors: David S Wack, Michael G Dwyer, Niels Bergsland, Deepa Ramasamy, Carol Di Perri, Laura Ranza, Sara Hussein, Christopher Magnano, Kevin Seals and Robert Zivadinov
    Citation: BMC Medical Imaging 2013 13:29
  30. Tubal and uterine cavity diseases commonly compromise female fertility. At the present time, hysteroscopy, laparoscopy with chromopertubation and RX-Hysterosalpingography (RX-HSG) are widely accepted screening...

    Authors: Roberto Marci, Immacolata Marcucci, Aurelio Aniceto Marcucci, Nicolina Pacini, Pietro Salacone, Annalisa Sebastianelli, Luisa Caponecchia, Giuseppe Lo Monte and Rocco Rago
    Citation: BMC Medical Imaging 2013 13:28
  31. The recently developed model-based iterative reconstruction (MBIR) enables significant reduction of image noise and artifacts, compared with adaptive statistical iterative reconstruction (ASIR) and filtered ba...

    Authors: Yasutaka Ichikawa, Kakuya Kitagawa, Naoki Nagasawa, Shuichi Murashima and Hajime Sakuma
    Citation: BMC Medical Imaging 2013 13:27
  32. Prostate cancer is one of the leading causes of cancer death in the male population. Fortunately, the prognosis is excellent if detected at an early stage. Hence, the detection and localization of prostate can...

    Authors: Alexander Wong, Jeffrey Glaister, Andrew Cameron and Masoom Haider
    Citation: BMC Medical Imaging 2013 13:26
  33. Fine needle aspiration biopsy is usually performed to evaluate thyroid lesions. The purpose of this study was to evaluate the usefulness of diffusion weighted imaging to differentiate malignancy of thyroid les...

    Authors: Yingwei Wu, Xiuhui Yue, Weiwen Shen, Yushan Du, Ying Yuan, Xiaofeng Tao and Cheuk Ying Tang
    Citation: BMC Medical Imaging 2013 13:23
  34. The frequency of CT procedures has registered a significant increase over the last decade, which led at the international level to an increasing concern on the radiological risk associated with the use of CT e...

    Authors: Abbas Aroua, Eleni-Theano Samara, François O Bochud, Reto Meuli and Francis R Verdun
    Citation: BMC Medical Imaging 2013 13:22
  35. The collagenous structure of menisci is a complex network of circumferentially oriented fascicles and interwoven radially oriented tie-fibres. To date, examination of this micro- architecture has been limited ...

    Authors: Stephen HJ Andrews, Janet L Ronsky, Jerome B Rattner, Nigel G Shrive and Heather A Jamniczky
    Citation: BMC Medical Imaging 2013 13:21
  36. Standard MRI has been used for high-grade gliomas detection, albeit with limited success as it does not provide sufficient specificity and sensitivity to detect complex tumor structure. Therefore targeted cont...

    Authors: Barbara Blasiak, Samuel Barnes, Tadeusz Foniok, David Rushforth, John Matyas, Dragana Ponjevic, Wladyslaw P Weglarz, Randy Tyson, Umar Iqbal, Abedelnasser Abulrob, Garnette R Sutherland, Andre Obenaus and Boguslaw Tomanek
    Citation: BMC Medical Imaging 2013 13:20
  37. Cardiac lipomatous metaplasia (LM) occurs in patients with chronic ischemic heart disease and heart failure with unclear mechanisms. We studied coronary occlusion/reperfusion-induced myocardial infarction (MI)...

    Authors: Yuanbo Feng, Feng Chen, Yi Xie, Huaijun Wang, Marlein Miranda Cona, Jie Yu, Junjie Li, Jan Bogaert, Stefan Janssens, Raymond Oyen and Yicheng Ni
    Citation: BMC Medical Imaging 2013 13:18
  38. A major challenge in the development of cell based therapies for glioma is to deliver optimal number of cells (therapeutic dose) to the tumor. Imaging tools such as magnetic resonance imaging (MRI), optical im...

    Authors: Nadimpalli Ravi S Varma, Adarsh Shankar, Asm Iskander, Branislava Janic, Thaiz Ferraz Borin, Meser M Ali and Ali S Arbab
    Citation: BMC Medical Imaging 2013 13:17
  39. Tissue Velocity Imaging (TVI) is an ultrasound based technique used for quantitative analysis of the cardiac function and has earlier been evaluated according to myocardial velocities. Recent years several stu...

    Authors: Frida Lindberg, Mattias Mårtensson, Christer Grönlund and Lars-Åke Brodin
    Citation: BMC Medical Imaging 2013 13:16
  40. Molecular imaging using magnetic nanoparticles (MNPs)—magnetic particle imaging (MPI)—has attracted interest for the early diagnosis of cancer and cardiovascular disease. However, because a steep local magneti...

    Authors: Yasutoshi Ishihara, Takumi Honma, Satoshi Nohara and Yoshio Ito
    Citation: BMC Medical Imaging 2013 13:15
  41. Carotid plaque echolucency as detected by Color Doppler ultrasonography (CDUS) has been used as a potential marker of plaque vulnerability. However, contrast-enhanced ultrasound (CEUS) has recently been shown ...

    Authors: Yangyang Zhou, Yingqi Xing, Yan Li, Yang Bai, Ying Chen, Xiaofeng Sun, Yingqiao Zhu and Jiang Wu
    Citation: BMC Medical Imaging 2013 13:13

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