Table 4 Receiver operating characteristic curve analysis of cyst volume, tumor volume, and C/T value in predicting Ki67 index and nuclear atypia
From: Predictive value of cyst/tumor volume ratio of pituitary adenoma for tumor cell proliferation
Parameter | Cutoff value | AUC | 95% CI | Sensitivity (%) | Specificity (%) | Youden index (%) | P value |
|---|---|---|---|---|---|---|---|
Ki67 index (≥ 3%) | |||||||
 Cyst volume | 0.188 | 0.701 | 0.576–0.833 | 72.00 | 74.47 | 0.467 | 0.004* |
 Tumor volume | 8.13 | 0.732 | 0.607–0.857 | 56.00 | 89.36 | 0.454 | 0.001* |
 C/T ratio | 0.159 | 0.808 | 0.710–0.914 | 88.00 | 68.09 | 0.561 | < 0.001** |
Nuclear atypia (presence) | |||||||
 Cyst volume | 0.148 | 0.646 | 0.513–0.786 | 64.29 | 75.00 | 0.392 | 0.034* |
 Tumor volume | 5.184 | 0.672 | 0.541–0.803 | 60.71 | 72.73 | 0.334 | 0.014* |
 C/T ratio | 0.159 | 0.743 | 0.637–0.862 | 78.57 | 65.91 | 0.445 | < 0.001** |