Table 2 Univariate analysis of factors associated with Ki67 index and nuclear atypia
From: Predictive value of cyst/tumor volume ratio of pituitary adenoma for tumor cell proliferation
| Â | Ki67 index | Nuclear atypia | ||||
|---|---|---|---|---|---|---|
Variables |  < 3% (n = 47) |  ≥ 3% (n = 25) | P value | Absent (n = 44) | Present (n = 28) | P value |
Median age, years (IQR) | 55.83 (44.92–63.45) | 53.91 (46.22–62.28) | 0.845 | 55.70 (47.10–66.10) | 54.87 (44.58–61.89) | 0.439 |
Number of male patients (%) | 22 (46.8%) | 10 (40.0%) | 0.580 | 22 (50.0%) | 10 (35.7%) | 0.234 |
Median cyst volume (IQR) (cm3) | 0.98 (0.14–2.89) | 0.10 (0.04–0.32) | 0.005* | 0.87 (0.15–2.51) | 0.10 (0.05–0.99) | 0.038* |
Median tumor volume (IQR) (cm3) | 4.12 (0.99–5.35) | 8.90 (3.41–12.07) | 0.001* | 4.12 (1.12–6.65) | 6.63 (2.35–12.39) | 0.014* |
Median C/T ratio (IQR) | 0.36 (0.11–0.70) | 0.02 (0.01–0.11) | < 0.001** | 0.36 (0.04–0.71) | 0.02 (0.01–0.16) | 0.001* |
Knosp grade (n [%]) | Â | Â | 0.611 | Â | Â | 0.858 |
 0 | 9 (19.1) | 3 (12.0) |  | 7 (15.9) | 5 (17.9) |  |
 1 | 14 (29.8) | 5 (20.0) |  | 13 (29.5) | 6 (21.4) |  |
 2 | 7 (14.9) | 6 (24.0) |  | 7 (15.9) | 6 (21.4) |  |
 3 | 7 (14.9) | 3 (12.0) |  | 7 (15.9) | 3 (10.7) |  |
 4 | 10 (21.3) | 8 (32.0) |  | 10 (22.7) | 8 (28.6) |  |