Fig. 3
From: Predictive value of cyst/tumor volume ratio of pituitary adenoma for tumor cell proliferation
Immunohistochemistry analysis of Ki67 and hematoxylin and eosin staining. A The representative image with a Ki67 index of < 3%. Most nuclei are blue-cyan, and a few are dark brown. B The representative image with a Ki67 index of ≥ 3%. The proportion of dark brown nuclei (blue arrow) is ≥ 3%. C The representative image with the absence of nuclear atypia. The nuclei have regular shapes and are not enlarged. D The representative image with the presence of nuclear atypia. The nuclei have irregular and inconsistent shapes and enlarged volume (blue arrow). Magnification: × 200. Scale bar: 50 μm