Altered trends of local brain function in classical trigeminal neuralgia patients after a single trigger pain

BMC Medical Imaging

Table 1 The static regional homogeneity difference in five frequency bands in CTN patients after triggering pain

Bands	Brain region	Side	Peak MNI coordinates			Cluster size (voxels)	Peak intensity	F value	P value	Post hoc P value
Bands	Brain region	Side	X	Y	Z	Cluster size (voxels)	Peak intensity	F value	P value	Baseline vs. 5 s	Baseline vs. 30 min	5 s vs. 30 min
Classical	ORBinf	R	45	-24	–15	167	14.307	32.152	0.000	0.000	0.353	0.000
	Calcarine	L	-24	-60	-6	989	17.429	11.688	0.000	0.148	0.000	0.000
	MOG	R	39	-87	0	191	27.354	22.704	0.000	0.000	0.000	0.003
	MFG	L	6	57	12	1262	20.011	32.378	0.000	0.000	0.000	0.122
	IFGtriang	R	63	12	12	238	14.555	36.949	0.000	0.000	0.375	0.000
	AnG	L	-42	-54	33	485	16.106	30.137	0.000	0.000	0.000	0.099
	Precuneus	L	0	-69	36	420	22.444	23.043	0.000	0.000	0.000	0.824
	MFG	R	36	45	39	158	15.272	23.383	0.000	0.004	0.000	0.000
	PCG	L	-24	-54	60	676	18.831	18.269	0.000	0.871	0.000	0.000
Slow 5	MOG	R	45	-75	-6	102	14.176	19.987	0.000	0.002	0.000	0.000
	MFG	L	-33	51	27	128	14.667	18.201	0.000	0.000	0.000	0.103
	Precuneus	L	0	-51	42	96	10.187	11.225	0.000	0.000	0.000	0.280
Slow 4	ORBinf	R	48	18	-18	259	14.269	40.362	0.000	0.000	0.108	0.000
	Calcarine	L	-15	-54	3	940	18.047	11.135	0.000	0.215	0.000	0.000
	MFG	L	-12	63	9	1053	21.368	37.574	0.000	0.000	0.000	0.078
	Precuneus	L	0	-66	36	488	21.142	21.134	0.000	0.000	0.000	0.126
	AnG	L	-51	-54	27	304	14.108	26.959	0.000	0.000	0.000	0.929
	PCG	L	-33	-27	51	731	17.263	19.105	0.000	0.786	0.000	0.000
Slow 3	Calcarine	L	0	-69	18	1144	19.932	12.598	0.000	0.176	0.000	0.000
	MFG	R	42	48	33	125	16.567	19.724	0.000	0.163	0.000	0.000
	SPG	L	-24	-54	60	124	19.087	17.073	0.000	0.665	0.000	0.000
Slow 2	SOG	L	-21	-90	27	52	12.117	10.138	0.000	0.965	0.000	0.000

CTN, Classical trigeminal neuralgia; MNI, Montreal Neurological Institute; Baseline, the rs-fMRI was performed before stimulating the trigger zone; 5 s, the rs-fMRI was performed within 5 s after stimulating the trigger zone; 30 min, the rs-fMRI was performed in the 30th minute after stimulating the trigger zone; ORBinf, inferior frontal gyrus, orbital part; MOG, Middle occipital gyrus; MFG, Middle frontal gyrus; AnG, angular gyrus; PCG, postcentral gyrus; IFGtriang, inferior frontal gyrus, triangular part; SOG, Superior occipital gyrus; SPG, Superior parietal gyrus; R, right; L, left

ISSN: 1471-2342