Development and validation of a multi-modal ultrasomics model to predict response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Table 6 DeLong testing between ultrasomics models and clinical model

Model	Training cohort			Validation cohort
Model	AUC (95%CI)	P-value in comparison to Clinical	P-value in comparison to Combined_1	AUC (95%CI)	P-value in comparison to Clinical	P-value in comparison to Combined_1
Clinical	0. 680 (0.561–0.784)	…	0.018	0.690 (0.503–0.841)	…	0.110
Combined_1	0.833 (0.740–0.927)	0.018	…	0.829 (0.673–0.985)	0.110	…
Combined_2	0.844 (0.757–0.932)	0.007	0.774	0.893 (0.780-1.000)	0.006	0.140

Combined_1: the integration of B-mode ultrasound and contrast-enhanced ultrasound; Combined_2: the integration of B-mode ultrasound, contrast-enhanced ultrasound, and deep learning; AUC: area under the curve; 95% CI: 95% confidence intervals. Statistical significance was demonstrated by P < 0.05

ISSN: 1471-2342