Table 4 Parameters of diagnostic performance
Model | Â | BUS | CEUS | Combined_1 | Combined_2 | Clinical |
|---|---|---|---|---|---|---|
Training cohort | AUC (95%CI) | 0.751 (0.640–0.862) | 0.714 (0.598–0.831) | 0.833 (0.740–0.927) | 0.844 (0.757–0.932) | 0.680 (0.569–0.792) |
Accuracy (%) | 71.6 | 67.6 | 78.4 | 79.7 | 67.7 | |
Sensitivity (%) | 73.0 | 70.3 | 67.6 | 75.7 | 78.4 | |
Specificity (%) | 70.3 | 64.9 | 89.2 | 83.8 | 56.8 | |
PPV (%) | 71.1 | 66.7 | 86.2 | 82.4 | 64.4 | |
NPV (%) | 72.2 | 68.6 | 73.3 | 77.5 | 72.4 | |
Validation cohort | AUC (95%CI) | 0.675 (0.481–0.868) | 0.821 (0.660–0.983) | 0.829 (0.673–0.985) | 0.893 (0.780-1.000) | 0.690 (0.509–0.872) |
Accuracy (%) | 68.8 | 81.2 | 78.1 | 84.4 | 71.9 | |
Sensitivity (%) | 57.1 | 64.3 | 92.9 | 78.6 | 78.6 | |
Specificity (%) | 77.8 | 94.4 | 66.7 | 88.9 | 66.7 | |
PPV (%) | 66.7 | 90.0 | 68.4 | 84.6 | 64.7 | |
NPV (%) | 70.0 | 77.3 | 92.3 | 84.2 | 80.0 |