Table 2 Univariable and multivariable logistic analysis of the clinical parameters

Age

 ≤ 60 (n = 77)

1 [Reference]

NA

1 [Reference]

NA

 > 60 (n = 29)

3.320 (1.309–8.417)

0.011

3.784 (1.429–10.018)

0.007

Sex

 Male(n = 72)

1 [Reference]

NA

-

-

 Female(n = 34)

1.064 (0.470–2.408)

0.881

-

-

Location (cm)

 ≤ 5(n = 64)

1 [Reference]

NA

-

-

 5–10(n = 42)

1.211(0.555–2.642)

0.631

-

-

Size (cm)

 ≤ 5(n = 81)

1 [Reference]

NA

-

-

 > 5(n = 25)

1.537(0.618–3.824)

0.355

-

-

Clinical stage

 II (n = 6)

1 [Reference]

NA

1 [Reference]

NA

 III (n = 80)

4.000(0,575-27.819)

0.161

6.130 (0.783–47.995)

0.084

 IV (n = 20)

4.889(1.501–15.924)

0.008

5.459 (1.626–18.328)

0.006

T stage

 T_1 − 2(n = 8)

1 [Reference]

NA

-

-

 T_3 − 4(n = 98)

1.884(0.427–8.321)

0.403

-

-

N stage

 N₀(n = 23)

1 [Reference]

NA

-

-

 N₊(n = 83)

1.231(0.488–3.103)

0.660

-

-

Distant-metastasis

 No(n = 86)

1 [Reference]

NA

-

-

 Yes(n = 20)

4.821(1.489–15.610)

0.009

-

-

CEA (ng/ml)

 ≤ 5(n = 49)

1 [Reference]

NA

-

-

 > 5(n = 57)

1.242(0.578–2.669)

0.579

-

-

CA199 (ng/ml)

 ≤ 35(n = 81)

1 [Reference]

NA

-

-

 > 35(n = 25)

1.006(0.410–2.468)

0.990

-

-

CA242 (U/ml)

 ≤ 20(n = 70)

1 [Reference]

NA

-

-

 > 20(n = 36)

1.025(0.394–2.667)

0.960

-

-