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Fig. 1 | BMC Medical Imaging

Fig. 1

From: A rapid multi-parametric quantitative MR imaging method to assess Parkinson’s disease: a feasibility study

Fig. 1

The flowchart of data processing. After image reconstruction, MULTIPLEX produces four kinds of quantitative parameters: T1, T2*, proton density, and QSM. The T1 map was non-linearly registered to the standard Montreal Neurological Institute coordinate space. Through the inverse non-linear transformation, all the subcortical nuclei were located in the subject’s space on corresponding T1, T2*, proton density, and QSM images according to the HybraPD atlas consisting of 12 human brain subcortical nuclei. The mean values of these four quantitative parameters were extracted from each subcortical nucleus. Afterward, ROI-based analyses were applied. HC: healthy control, PD: Parkinson’s disease, QSM: quantitative susceptibility mapping, T1WI: T1-weighted image, MNI: Montreal Neurological Institute

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BMC Medical Imaging

ISSN: 1471-2342

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