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Table 3 Multivariate analysis with logistic regression in the MRI imaging features

From: A gadoxetic acid-enhanced MRI-based model using LI-RADS v2018 features for preoperatively predicting Ki-67 expression in hepatocellular carcinoma

Characteristic

Multivariate analysis

B

P

OR (95%CI)

20% of Ki-67 cutoff

 Nonperipheral washout

-0.794

0.285

0.452 (0.105–1.938)

 Mosaic architecture

0.796

0.077

2.216 (0.918–5.350)

 Rim APHE

19.08

0.998

1.93 × 108 (0)

 Targetoid restriction

19.439

0.998

2.77 × 108 (0)

 Peritumoral enhancement

18.844

0.998

1.53 × 108 (0)

30% of Ki-67 cutoff

 Nodule in nodule

-0.269

0.734

0.764 (0.162–3.599)

 Mosaic architecture

0.897

0.251

2.453 (0.531–11.339)

 Corona enhancement

0.826

0.505

2.285 (0.201–25.908)

 Rim APHE

20.436

0.998

7.5 × 108 (0)

 Delayed central enhancement

19.197

0.999

2.17 × 108 (0)

 Targetoid restriction

0.082

0.935

1.086 (0.148–7.979)

 Satellite nodules

0.207

0.680

1.23 (0.459–3.294)

 Portal and hepatic vein tumor thrombus

0.657

0.307

1.93 (0.547–6.805)

 Peritumoral enhancement

0.703

0.569

2.02 (0.179–22.736)

50% of Ki-67 cutoff

 Size (≥ 5 cm)

-0.852

0.280

0.427(0.091–2.003)

 Nodule in nodule

0.862

0.365

2.367(0.367–15.28)

 Mosaic architecture

1.706

0.045*

5.507(1.036–29.271)

 Blood products in mass

0.149

0.810

1.16(0.346–3.895)

 Mild to moderate T2 hyperintensity

-21.537

0.999

0(0)

 Corona enhancement

2.195

0.078

8.983(0.785–102.793)

 Targetoid HBP

-1.304

0.035*

0.271(0.081–0.915)

 Infiltrated appearance

1.141

0.039*

3.129(1.058–9.258)

 Portal and hepatic vein tumor thrombus

0.108

0.862

1.114(0.330–3.764)

 Peritumoral enhancement

0.309

0.776

1.362(0.163–11.381)

  1. Abbreviations: APHE arterial phase hyperenhancement, B regression coefficients, CI confidence interval, HBP hepatobiliary phase, OR odds ratio*p < 0.05
  2. *p < 0.05