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Table 4 ADC values (mean ± standard deviation) and ratios with 95%-confidence interval

From: Differentiation of multiple brain metastases and glioblastoma with multiple foci using MRI criteria

Parameter

Multiple brain metastases

mGBM

Multifocal

mGBM

Multicentric

mGBM

Mixed

mGBM

ADC-value (tumor)

673 ± 305

721 ± 323

742 ± 296

796 ± 262

685 ± 352

ADC-value (edema 5 mm)

1512 ± 276*

1227 ± 526

1353 ± 501

1391 ± 322

1066 ± 323*

ADC-value (edema 10 mm)

1593 ± 305

1498 ± 466

1642 ± 329*

1554 ± 387

1343 ± 387*

ADC-value (edema 20 mm)

1653 ± 307

1561 ± 584

1816 ± 307

1684 ± 279

1296 ± 279

ADC-ratio (tumor)

0.97 ± 0.48

(0.87–1.07)

1.05 ± 0.35

(0.99–1.11)

0.98 ± 0.34

(0.88–1.08)

1.06 ± 0.41

(0.89–1.24)

1.09 ± 0.34

(1.01–1.17)

ADC-ratio (edema 5 mm)

2.17 ± 0.41**

(2.08–2.25)

1.79 ± 0.54

(1.67–1.91)

1.83 ± 0.52

(1.63–2.03)

1.88 ± 0.55

(1.55–2.21)

1.72 ± 0.56

(1.53–1.91)

ADC-ratio (edema 10 mm)

2.25 ± 0.41

(2.16–2.35)

2.07 ± 0.55

(1.91–2.23)

2.11 ± 0.48

(1.89–2.33)

2.02 ± 0.66

(1.41–2.63)

2.05 ± 0.59

(1.78–2.32)

ADC-ratio (edema 20 mm)

2.36 ± 0.47

(2.23–2.49)

2.28 ± 0.51

(2.07–2.49)

2.34 ± 0.45

(1.99–2.68)

2.24 ± 0.61

(1.48–2.99)

2.25 ± 0.55

(1.88–2.62)

  1. mGBM Glioblastoma with multiple foci at presentation, BM Brain metastases, ADC Apparent diffusion coefficient, edemas were measured in 5, 10 and 20 mm distance (if available) from the contrast enhancing tumor. * -differs significantly p < .05 from some other groups with t-Test; ** -differs significantly p < .05 from all other groups with t-Test