Table 2 Baseline characteristics of study population
From: Differentiation of multiple brain metastases and glioblastoma with multiple foci using MRI criteria
Parameter | GBM with multiple tumor lesions | Multiple brain metastases | p-value binomial test |
|---|---|---|---|
Number of patients | 50 | 50 | |
Mean age ± SD | 65 ± 13 | 66 ± 10 | |
Sex | |||
Male (%) | 34/50 (68%) | 27/50 (54%) | |
Female (%) | 16/50 (32%) | 23/50 (46%) | |
Histology | |||
Lung cancer | 30/50 (60%) | ||
Breast cancer | 7/50 (14%) | ||
Melanoma | 7/50 (14%) | ||
Colorectal cancer | 2/50 (4%) | ||
Gastric cancer | 1/50 (2%) | ||
Ovarian cancer | 1/50 (2%) | ||
Transitional cell carcinoma | 1/50 (2%) | ||
Clear cell renal cancer | 1/50 (2%) | ||
Mean number of tumor lesions ± SD; (range) per patient | 3.6 ± 1.5 (2–7) | 4.2 ± 2.3 (2–10) | |
Total number of lesions | 181 | 210 | |
Location of tumor lesions | |||
Frontal white matter | 48/181 (27%) | 64/210 (30%) | 0.47 |
Parietal white matter | 22/181 (12%) | 25/210 (12%) | 0.47 |
Temporal white matter | 40/181 (22%) | 34/210 (16%) | 0.26 |
Occipital white matter | 8/181 (4%) | 22/210 (10%) | < 0.001 |
Diencephalon | 18/181 (10%) | 2/210 (1%) | < 0.0001 |
Brain stem | 4/181 (2%) | 1/210 (0.5%) | 0.09 |
Cerebellum | 1/181 (0.5%) | 59/210 (28%) | < 0.0001 |
Corpus callosum | 22/181 (12%) | 0/210 (0%) | < 0.0001 |
Septum pellucidum | 2/181 (1%) | 0/210 (0%) | 0.11 |
Basal ganglia | 8/181 (4%) | 2/210 (1%) | 0.12 |
Insula | 4/181 (2%) | 0/210 (0%) | 0.03 |
Ependym | 1/181 (0.5%) | 1/210 (0.5%) | 0.33 |
Total number of lesions | 181 | 210 | |