Threshold growth has a limited role in differentiating hepatocellular carcinoma from other focal hepatic lesions

BMC Medical Imaging

Table 6 Diagnostic performance of LI-RADS protocols for HCC

	Sensitivity	Specificity	PPV	NPV	Accuracy	Youden
LI-RADS v2018	74.4%	88.6%	90.3%	70.9%	80.3%	0.630
Scheme A	74.0%	88.6%	90.2%	70.6%	80.0%	0.540
Scheme B	75.6%	88.6%	90.4%	71.9%	81.0%	0.642
P _a value	> 0.999	> 0.999	—	—	> 0.999	—
P _b value	0.375	> 0.999	—	—	0.375	—

Schemes A and B are described in Table 5. P_a values are for comparisons of diagnostic performance between scheme A and LI-RADS v2018 using McNemar’s test, andP_b values are for comparisons of diagnostic performance between scheme B and LI-RADS v2018 using McNemar’s test. PPV, positive predictive value; NPV, negative predictive value

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