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Table 4 Severity scoring of CXR in pediatric patients with COVID-19

From: Radiographic patterns and severity scoring of COVID-19 pneumonia in children: a retrospective study

Variable (n, %)

Total N= 106

Severity score of abnormal CXR findings

p-value

Mild (n = 81)

Moderate (n = 21)

Severe (n = 4)

Treatment

 Favipiravir, n (%)

34 (32.1%)

24 (29.6%)

7 (33.3%)

3 (75%)

0.177

 Antibiotic, n (%)

9 (8.5%)

3 (3.7%)

3 (14.3%)

3 (75%)

 < 0.001*

 Steroid, n (%)

10 (9.4%)

4 (4.9%)

3 (14.3%)

3 (75%)

 < 0.001*

 Remdesivir, n (%)

9 (8.5%)

3(3.7%)

3 (14.3%)

3 (75%)

 < 0.001*

 Required oxygen support, n (%)

5 (4.7%)

1 (1.2%)

2 (9.5%)

2 (50%)

0.002*

Cycle threshold of RT-PCR SARS-

 CoV-2 (n = 22)a

    

N/A

ORF-gene, mean (SD)

22.6 (6.1)

23.4 (6.7)

22.4 (5.3)

18.8 (5.1)

 

N-gene, mean (SD)

21.1 (5.9)

20.8 (6.7)

23.1 (4.3)

16.8 (2.4)

 

Follow-up CXR (n, %)

Total N= 40

Severity score of abnormal CXR findings

p-value

Mild (n= 28)

Moderate (n= 9)

Severe (n= 3)

Resolution

25(62.5%)

17 (60.7%)

6 (66.7%)

2 (66.7%)

1.000

Progression

6 (15.4%)

4 (14.3%)

1 (11.1%)

1 (33.3%)

0.387

Stable

4 (10.3%)

3 (10.7%)

1 (11.1%)

0 (0%)

1.000

Normal initial CXR findings later became abnormal

5 (12.8%)

4 (14.3%)

1 (11.1%)

0 (0%)

1.000

  1. CXR Chest radiography, COVID-19 Coronavirus disease-19, N/A Not applicable, RT-PCR, Reverse transcriptase-polymerase chain reaction, ORF Open reading frame, SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2, SD Standard deviation
  2. *Statistical significance p-value ≤ 0.05.
  3. aLarge proportion of missing data in the cycle threshold of RT-PCR SARS-CoV-2 (84 of 106 cases)