Table 3 Significance areas for covariates in the MUR model between the anthropometric covariates and liver IDPs (N = 33,434) in model 2. The total area has been split into areas of positive and negative associations. The regression coefficients are presented as median (interquartile range - IQR) and the significance areas as a percentage (%) of the vertices
From: Liver shape analysis using statistical parametric maps at population scale
| Â | \(\widehat{\boldsymbol\beta }\boldsymbol<\,0\) | \(\widehat{\boldsymbol\beta }\boldsymbol>\,0\) | Total | ||
|---|---|---|---|---|---|
Beta coefficients | Significance area | Beta coefficients | Significance area | Significance area | |
Age (yrs.) | -0.11 (0.06) | 96.63% | 0.02 (0.04) | 1.46\(\%\) | 98.10\(\%\) |
BMI (kg/m2) | -0.08 (0.07) | 1.61% | 0.30 (0.22) | 97.82\(\%\) | 99.43\(\%\) |
WHR | -3.88 (4.02) | 33.99\(\%\) | 3.87 (3.65) | 58.11\(\%\) | 92.10\(\%\) |
AST:ALT | -0.32 (0.32) | 35.17% | 0.30 (0.29) | 48.05% | 83.22\(\%\) |
FIB-4 | -0.22 (0.17) | 82.62% | 0.23 (0.13) | 2.09% | 84.70\(\%\) |
Liver PDFF (%) | -0.03 (0.02) | 0.17\(\%\) | 0.26 (0.10) | 99.65\(\%\) | 99.82\(\%\) |
Liver Iron (mg/g) | -0.59 (0.74) | 58.00\(\%\) | 0.34 (0.32) | 24.99\(\%\) | 82.98% |
Liver disease | -2.13 (2.95) | 21.90\(\%\) | 1.95 (2.43) | 25.14\(\%\) | 47.05% |
T2D | -0.61 (0.77) | 5.35\(\%\) | 2.42 (1.94) | 86.40\(\%\) | 91.76\(\%\) |
Age * Liver disease | ns | ns | ns | ns | ns |
Liver PDFF *Â Liver disease | -0.09 (0.01) | 0.09% | 0.09 (0.03) | 12.59% | 12.68% |
Age * T2D | -0.03 (0.02) | 71.23% | 0 | 0% | 71.23% |
Liver PDFF * T2D | -0.06 (0.04) | 6.24% | 0.10 (0.08) | 82.84% | 89.08% |