Table 4 The detailed MRI and 18F-FDG PET/CT (through Scenium analysis) results of AE patients

1

NMDAR

Female

36

Right cerebrum, brainstem, right thalamus and basal ganglia

Right supplementary motor area and middle cingulate

Right frontal, temporal, parietal, occipital lobes and left parietal lobe

2

NMDAR

Male

34

Right frontal, parietal, temporal lobe, especially temporal lobe

Right frontal, temporal, insula lobe and anterior and middle cingulate left hippocampus and brainstem

Bilateral parietal lobe and occipital lobe, left frontal lobe

3

NMDAR

Female

13

Normal

—

4

NMDAR

Female

14

Demyelination

—

5

NMDAR

Male

25

—

—

6

NMDAR

Female

25

Normal

—

7

LGI1

Female

64

Left temporal and occipital lobe, left hippocampus and brainstem

Bilateral basal ganglia, amygdala, hippocampus, para- hippocampus and anterior cingulate

8

LGI1

Female

56

Normal

—

9

LGI1

Male

67

Normal

—

10

LGI1

Female

61

Normal

—

11

LGI1

Male

54

Normal

Bilateral basal ganglia, amygdala, hippocampus, para- hippocampus and anterior cingulate

12

LGI1

Female

40

Normal

Bilateral basal ganglia, amygdala, hippocampus, para- hippocampus and anterior cingulate

13

LGI1

Male

54

Bilateral hippocampus, insula and temporal lobe

Bilateral hippocampus and insula

14

LGI1

Male

55

Normal

Bilateral hippocampus and insula

15

GABABR

Male

41

Left hippocampus, basal ganglia and temporal lobe

—

16

GABABR

Male

66

Bilateral hippocampus, insula and temporal lobe

Bilateral basal ganglia, amygdala, hippocampus, para- hippocampus

17

GABABR

Female

56

Normal

Bilateral basal ganglia, amygdala, hippocampus, para-hippocampus, anterior and middle cingulate, right insula and inferior frontal gyrus

18

GABABR

Male

64

Normal

Bilateral hippocampus and thalamus

19

GABABR

Male

57

Normal

Bilateral basal ganglia, amygdala, hippocampus, para-hippocampus

20

HU

Female

55

Normal

Bilateral basal ganglia, amygdala, left hippocampus, para- hippocampus, bilateral anterior cingulate, right central region and right gyrus rectus and cuneus gyrus

21

HU

Female

67

Normal

Normal

22

HU

Male

77

Normal

Bilateral basal ganglia, amygdala, left hippocampus, para- hippocampus, right orbital gyrus, bilateral central region and anterior central gyrus and brainstem

23

HU

Female

60

Normal

Bilateral basal ganglia

24

SOX1 and HU

Female

51

Bilateral hippocampus, left insula and temporal lobe

Bilateral basal ganglia, amygdala, hippocampus, para- hippocampus, left paracentral lobe and brainstem

25

SOX1 and HU

Female

63

Normal

Bilateral amygdala, hippocampus, para-hippocampus, left paracentral lobe, left lingual gyrus and bilateral occipital lobe

26

HU and RI

Female

66

Normal

Bilateral cingulate gyrus

27

GAD65-Ab + 

Female

64

Bilateral hippocampus, insula and temporal lobe

Bilateral amygdala, hippocampus

28

GAD65-Ab + 

Female

55

Normal

Bilateral parietal and occipital lobe, bilateral paracentral lobe, left hippocampus, para-hippocampus

29

PNMA2 + /Ma2/Ta

Female

48

Left temporal and parietal lobe, left insula and hippocampus

Bilateral amygdala, hippocampus, para-hippocampus, insula and anterior central gyrus, left basal ganglia, cingulate gyrus, olfactory cortex

Left temporal and parietal lobe

30

Amphiphysin

Male

63

Normal

Bilateral occipital lobe and thalamus, anterior central gyrus

31

CASPR2

Male

55

Normal

—

—

32

GFAP

Female

35

Right temporal and occipital lobe, right cerebellum

—

—