Predictive value of Dmax and %ΔSUVmax of 18F-FDG PET/CT for the prognosis of patients with diffuse large B-cell lymphoma

Table 3 ROC analysis of PET parameters to PFS

Variables	AUC	P	cutoff value	Sensitivity (%)	Specificity (%)
SUVmax0	0.483	0.758	28.07	77.1	34.5
TMTV0	0.618	0.035	152.11	82.9	46.2
STMTV0	0.619	0.033	2.63	82.9	47.9
TTLG0	0.585	0.127	799.63	82.9	41.2
STTLG0	0.580	0.149	13.38	82.9	39.5
Dmax	0.707	< 0.001	53.20	51.4	82.4
SUVmax1	0.664	0.003	5.31	48.6	86.6
TMTV1	0.628	0.021	30.03	28.6	95.8
TTLG1	0.649	0.008	78.97	34.3	93.3
%ΔSUVmax	0.686	0.001	87.82	77.1	57.1
%ΔTMTV	0.572	0.195	95.37	42.9	78.2
%ΔTTLG	0.594	0.092	98.41	40.0	79.8

AUC, area under the receiver operating characteristic curve; SUVmax, maximum standardized uptake value; MTV, metabolic tumor volume; TLG, total lesion glycolysis; Dmax, defined as the distance between the two lesions that were the furthest apart. The subscripts 0 and 1 represent baseline and interim measures, respectively

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