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Table 1 Demographic Characteristics and Meningioma Information

From: Changes in radiomic and radiologic features in meningiomas after radiation therapy

Variable

Observation group (n = 100)

Treatment group (n = 62)

P Value

Patient age (y)*

69 ± 12 (40 ~ 98)

64 ± 10 (43 ~ 83)

< 0.001

No. of men

No. of women

27 (27)

73 (73)

15 (24.2)

47 (75.8)

0.57

Follow up period (y)*

2.9 ± 2.5

3.0 ± 2.3

0.87

Post treatment period (y)*

2.6 ± 2.2

0.38

Total radiation dose†

0

1400 (400–2800)

 

Location (No.) (%)

  

< 0.0001

Parasagittal or falx cerebri

76 (76)

32 (51.6)

 

Anterior cranial fossa

6 (6)

2 (3.2)

Cerebellopontine angle

3 (3)

9 (14.5)

Cerebellar tentorium

3 (3)

1 (1.6)

Cavernous sinus

2 (2)

3 (4.8)

Posterior fossa

2 (2)

6 (9.7)

Olfactory bulb

2 (2)

3 (4.8)

Lateral ventricle

2 (2)

2 (3.2)

Middle cranial fossa

2 (2)

1 (1.6)

Prepontine cistern

1 (1)

0 (0)

Foramen magnum

1 (1)

0 (0)

Sella

0 (0)

1 (1.6)

Straight sinus

0 (0)

1 (1.6)

Optic sheath

0 (0)

1 (1.6)

Imaging features (No.) (%)

Description

   

CSF cleft

Perimeter of CSF between the tumor and brain

88 (88)

47 (75.2)

< 0.001

Mass effect

Shift in normal brain parenchyma due to tumor

25 (25)

23 (36.8)

0.02

Intratumoral heterogeneity

Heterogeneity in hyperintensity of MRI signal throughout tumor

22 (11)

7 (11.2)

0.87

Skull hyperostosis

Bony overgrowth adjacent to tumor

14 (14)

14 (22.4)

0.07

Multifocality

Non-contiguous growth of tumor

5 (5)

3 (4.8)

0.95

Bony invasion

Appearance of tumor invading the skull

3 (3)

12 (19.2)

< 0.0001

Midline shift

Shift of the brain past midline

3 (3)

3 (4.8)

0.26

Necrosis/Hemorrhage

Presence of necrosis or hemorrhage

3 (3)

5 (8.0)

0.04

Spiculation

Irregularities in tumor shape and border

3 (3)

3 (4.8)

0.39

Cystic component

Fluid filled cysts within the tumor

3 (3)

2 (3.2)

0.76

Sinus invasion

Presence of venous sinus invasion

2 (2)

10 (16)

< 0.0001

Recurrence

Recurrent at presentation

1 (1)

4 (6.4)

0.01

  1. Note: Unless otherwise specified, data are numbers of patients, with percentages in parentheses. Categoric variables were compared using the χ2 test or the Fisher exact test, as appropriate. Continuous variables were compared using the Mann-Whitney U test
  2. * Data are expressed as means ± standard deviations; data in parentheses are ranges
  3. † Data are expressed as medians, with ranges in parentheses