Differentiating tumour progression from pseudoprogression in glioblastoma patients: a monoexponential, biexponential, and stretched-exponential model-based DWI study

Table 3 Diagnostic performance for the differentiation between tumour progression and pseudoprogression

Parameters	AUC	95% CI	Cut-off values	Youden index	Sensitivity (%)	Specificity (%)
ADC	0.91	0.81–0.98	1.61	0.78	92.45	83.33
D	0.92	0.84–0.99	1.28	0.86	86.36	86.45
D*	0.81	0.65–0.91	38.21	0.67	72.73	84.44
f	0.75	0.58–0.87	0.21	0.47	86.36	61.11
DDC	0.88	0.73–0.95	1.45	0.68	90.91	77.78
α	0.94	0.81–0.99	0.78	0.79	95.91	88.89

Abbreviations: ADC Apparent diffusion coefficient, D true diffusion coefficient, D* perfusion-related pseudodiffusion coefficient, DDC Distributed diffusion coefficient, f perfusion fraction, α diffusion heterogeneity index, AUC Area under the receiver operating characteristic curve, CI Confidence interval

ISSN: 1471-2342