Differentiating tumour progression from pseudoprogression in glioblastoma patients: a monoexponential, biexponential, and stretched-exponential model-based DWI study

Table 2 Discrimination and reliability of the multi-b DWI parameters in differentiating tumour progression from pseudoprogression

Parameters	Tumour progression	Pseudoprogression	t value	p value	ICC
ADC (× 10^–3 s/mm²)	1.315 ± 0.175	1.956 ± 0.306	8.309	0.001*	0.734
D (× 10^–3 s/mm²)	1.084 ± 0.126	1.741 ± 0.213	12.118	0.001*	0.700
D* (× 10^–3 s/mm²)	53.841 ± 26.578	25.613 ± 8.951	4.305	0.001*	0.887
f	0.333 ± 0.108	0.239 ± 0.086	2.962	0.005*	0.622
DDC (× 10^–3 s/mm²)	1.177 ± 0.397	1.692 ± 0.350	4.300	0.001*	0.700
α	0.673 ± 0.092	0.879 ± 0.091	7.084	0.001*	0.757

Data are means ± standard deviations
Comparisons were performed by independent samples t test
Abbreviations: ADC Apparent diffusion coefficient, D true diffusion coefficient, D* perfusion-related pseudodiffusion coefficient, f perfusion fraction, DDC Distributed diffusion coefficient, α diffusion heterogeneity index
^*Denotes p values that are significant (in bold)

ISSN: 1471-2342