Fig. 6

A Intervention avoidance curves in the development cohort. For example, with a probability threshold of 15%, the net reduction in interventions is approximately 14 per 100 patients by using the clinical model. In other words, at this probability threshold, the biopsies of patients on the basis of the clinical model are the equivalent of a strategy that reduced the biopsy rate by 14% without missing any cancers. The net reduction in interventions was approximately 32 per 100 patients by using the bpMRI PI-RADS v2.1-based model with a probability threshold of 15%. B Intervention avoidance curves in validation cohort 1. C Intervention avoidance curves in validation cohort 2. PI-RADS v2.1 = Prostate Imaging Reporting and Data System version 2.1; bpMRI = biparametric Magnetic Resonance Imaging