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Table 5 Comparison of classification performance by hot spot size in “BUS+CEUS”. All units except AUROC are in percent. Values in parentheses are 95 % confidence interval

From: Ceusia-Breast: computer-aided diagnosis with contrast enhanced ultrasound image analysis for breast lesions

Hot spot size (mm)

2

3

4

5

Entire tumor

Number of selected features

7

13

12

12

13

AUROC

0.875 (0.795 - 0.936)

0.865 (0.795 - 0.926)

0.862 (0.791 - 0.928)

0.865 (0.791 - 0.934)

0.868 (0.791 - 0.934)

ACC

0.816 (0.750 - 0.883)

0.805 (0.750 - 0.867)

0.803 (0.750 - 0.867)

0.814 (0.750 - 0.867)

0.809 (0.750 - 0.867)

Precision (PPV)

0.841 (0.764 - 0.905)

0.838 (0.765 - 0.900)

0.834 (0.764 - 0.897)

0.842 (0.769 - 0.905)

0.835 (0.774 - 0.889)

Recall (Sensitivity)

0.920 (0.814 - 1.000)

0.907 (0.814 - 1.000)

0.909 (0.814 - 1.000)

0.915 (0.814 - 1.000)

0.918 (0.814 - 1.000)

F1

0.877 (0.828 - 0.921)

0.869 (0.822 - 0.913)

0.869 (0.824 - 0.911)

0.876 (0.825 - 0.913)

0.873 (0.828 - 0.913)

Specificity

0.550 (0.235 - 0.765)

0.548 (0.235 - 0.765)

0.536 (0.235 - 0.765)

0.558 (0.294 - 0.765)

0.535 (0.294 - 0.706)

NPV

0.749 (0.562 - 1.000)

0.718 (0.550 - 1.000)

0.720 (0.555 - 1.000)

0.740 (0.556 - 1.000)

0.737 (0.562 - 1.000)

  1. Bold numbers indicate the best hot spot size within each metric