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Table 4 Comparison of classification performance by hot spot size in “CEUS”. All units except AUROC are in percent. Values in parentheses are 95 % confidence interval

From: Ceusia-Breast: computer-aided diagnosis with contrast enhanced ultrasound image analysis for breast lesions

Hot spot size (mm)

2

3

4

5

Entire tumor

Number of selected features

5

4

4

4

16

AUROC

0.862 (0.792 - 0.924)

0.855 (0.780 - 0.922)

0.847 (0.776 - 0.912)

0.851 (0.776 - 0.919)

0.856 (0.778 - 0.921)

ACC

0.788 (0.717 - 0.850)

0.795 (0.733 - 0.850)

0.790 (0.733 - 0.850)

0.796 (0.733 - 0.850)

0.797 (0.733 - 0.850)

Precision (PPV)

0.825 (0.754 - 0.902)

0.832 (0.759 - 0.895)

0.824 (0.750 - 0.889)

0.831 (0.760 - 0.889)

0.825 (0.759 - 0.889)

Recall (Sensitivity)

0.898 (0.814 - 1.000)

0.897 (0.791 - 1.000)

0.903 (0.814 - 1.000)

0.902 (0.814 - 1.000)

0.913 (0.814 - 1.000)

F1

0.858 (0.817 - 0.899)

0.862 (0.817 - 0.901)

0.860 (0.818 - 0.897)

0.863 (0.815 - 0.903)

0.865 (0.824 - 0.905)

Specificity

0.510 (0.176 - 0.765)

0.535 (0.235 - 0.765)

0.502 (0.176 - 0.765)

0.527 (0.235 - 0.765)

0.504 (0.235 - 0.706)

NPV

0.680 (0.500 - 1.000)

0.692 (0.529 - 1.000)

0.693 (0.526 - 1.000)

0.703 (0.529 - 1.000)

0.712 (0.545 - 1.000)

  1. Bold numbers indicate the best hot spot size within each metric