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Table 1 Comparison of Ki67 status and characteristics in both training and test HCC patients

From: Added value of CE-CT radiomics to predict high Ki-67 expression in hepatocellular carcinoma

Characteristic

Model derivation and verification

Model application

P

Training set (n = 120)

Internal test set (n = 51)

External validation set (n = 37)

Sex

   

0.255

 Male

105

41

27

 

 Female

15

10

10

 

Age

56.55 ± 9.53

56.14 ± 10.82

58.32 ± 9.88

0.804

Etiology

   

0.606

 HBV/HCV

107

47

19

 

 None or other

13

4

18

 

Serum AFP

   

0.995

  Normal

47

20

8

 

  Abnormal

73

31

29

 

Total bilirubin (nmol/L)

17.15(11.43–32.04)

17.11(11.71–31.15)

15.8(12.0–19.75)

0.828

ALB(g/l)

37.85(32.00–42.10)

37.80(31.80–42.10)

43.5(39.55–45.05)

0.412

CA199(ng/ml)

19.89(10.44–45.11)

19.90(13.42–46.1)

16.84(10.59–26.21)

0.446

CEA (ng/ml)

2.53(1.78–3.69)

2.63(1.89–3.65)

2.11(1.61–4.13)

0.056

  1. HBV hepatitis B varus, HCV hepatitis C varus, AFP α-fetoprotein, ALB albumin, CA-199 carbohydrate antigen19-9, CEA carcino embryonie antigen