Direct comparison of diagnostic and clinical values between Tc-99 m DPD and Tc-99 m PYP scintigraphy in patients with cardiac amyloidosis

Table 4 Significant associations between scintigraphic parameters and clinical variables in DPD and PYP scans

Scintigraphy	Scintigraphic parameter	Clinical variable	rho^†	P value
DPD	DPD H/WBp	Age	0.745	0.0133^*†
		NT-proBNP	0.840	0.0023^*†
		EchoCG		0.0356^*‡
		EMG		0.0356^*‡
	DPD H/P	EchoCG		0.0367^*‡
		EMG		0.0367^*‡
	DPD H/S	NT-proBNP	0.802	0.0053^*†
		EchoCG		0.0367^*‡
		EMG		0.0367^*‡
	DPD H/CL	Age	0.726	0.0175^*†
		NT-proBNP	0.673	0.0330^*†
		EchoCG		0.0367^*‡
		EMG		0.0367^*‡
	DPD Perugini	EchoCG		0.0182^*‡
		EMG		0.0182^*‡
	DPD Dorbala	Age	0.696	0.0253^*†
		eGFR	-0.701	0.0240^*†
		NT-proBNP	0.701	0.0240^*†
		EchoCG		0.0029^*‡
		EMG		0.0029^*‡
PYP	PYP H/WBp	Age	0.659	0.0384^*†
		EchoCG		0.0367^*‡
		EMG		0.0367^*‡
	PYP H/S	Age	0.634	0.0489^*†
		EchoCG		0.0367^*‡
		EMG		0.0367^*‡
	PYP H/CL	Age	0.696	0.0253^*†
		eGFR	-0.685	0.0289^*†
	PYP Perugini	NT-proBNP	0.724	0.0180^*†

Abbreviations: DPD, technetium-99 m 3,3-diphosphono-1,2-propanodicarboxylic acid; PYP, technetium-99 m pyrophosphate; H/WBp, heart/whole-body profile; NT-proBNP, N-terminal pro brain natriuretic peptide; EchoCG, echocardiography; EMG, electromyography; H/P, heart/pelvis; H/S, heart/skull; H/CL, heart/contralateral lung; eGFR, estimated glomerular filtration rate. ^* P < 0.05. ^† Spearman’s correlation. ^‡ Mann-Whitney U test

ISSN: 1471-2342