Direct comparison of diagnostic and clinical values between Tc-99 m DPD and Tc-99 m PYP scintigraphy in patients with cardiac amyloidosis

Table 2 Scintigraphic findings in the DPD and PYP scans

		DPD scan	PYP scan
		Median (range) or number of patients	Median (range) or number of patients	P value^†	rho^‡	P value^‡
WB tracer retention		2,534,500 (1,730,000–2,905,000)	3,256,000 (1,590,000–4,466,000)	0.0696	0.612	0.0600
Heart tracer retention		117,892 (7,900 − 364,705)	163,222 (69,068–236,805)	0.3258	0.600	0.0667
Retention ratio	H/WBp	0.062 (0.006–0.157)	0.068 (0.034–0.092)	0.7052	0.841	0.0023^*
	H/P	0.827 (0.095–2.649)	0.948 (0.520–1.552)	0.3845	0.879	0.0008^*
	H/S	0.920 (0.054–2.727)	0.749 (0.349–1.236)	0.4057	0.915	0.0002^*
	H/CL	20.646 (7.335–40.264)	21.133 (9.603–32.970)	0.7624	0.952	< 0.0001^*
Visual score	Perugini score (0/1/2/3)	1/1/2/6	0/1/4/5	0.8996	0.852	0.0017^*
	Dorbala score (0/1/2/3)	1/1/0/8	0/0/2/8	0.8287	0.435	0.2092

Abbreviations: DPD, technetium-99 m 3,3-diphosphono-1,2-propanodicarboxylic acid; PYP, technetium-99 m pyrophosphate; WB, whole-body; H/WBp, heart/whole-body profile; H/P, heart/pelvis; H/S, heart/skull; H/CL, heart/contralateral lung. ^* P < 0.05. ^† Mann-Whitney U test. ^‡ Spearman’s correlation

ISSN: 1471-2342