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Table 1 Characteristics of included BC patients with different AR expression statuses

From: Assessment of androgen receptor expression in breast cancer patients using 18 F-FDG PET/CT radiomics and clinicopathological characteristics

Characteristics

AR- (n = 15)

AR+ (n = 33)

t/x2/z

p-value

Age (years)

56.00 ± 15.28

53.70 ± 13.74

0.520

0.606

BMI (kg/m2)

24.69 ± 4.25

24.82 ± 4.02

0.100

0.921

Menopausal Status

  

0.162

0.688

 Premenopausal

5(33.3%)

13(39.4%)

  

 Postmenopausal

10(66.7%)

20(60.6%)

  

Tumor Location

  

0.014

0.907

 Left

8(53.3%)

17(51.5%)

  

 Right

7(46.7%)

16(48.5%)

  

Histologic Type

  

0.514

0.662

 IDC

12(80.0%)

29(87.9%)

  

 Other

3(20.0%)

4(12.1%)

  

Clinical Stage

  

0.730

0.393

 I-II

4(26.7%)

13(39.4%)

  

 III-IV

11(73.3%)

20(60.6%)

  

Clinical T Stage

  

0.183

0.738

 T1-T2

10(66.7%)

24(72.7%)

  

 T3-T4

5(33.3%)

9(27.3%)

  

Clinical N Stage

  

1.302

0.629

 N0

4(26.7%)

14(42.4%)

  

 N1-2

6(40.0%)

9(27.3%)

  

 N3

5(33.3%)

10(30.3%)

  

Clinical M Stage

  

0.032

1.000

 M0

11(73.3%)

25(75.8%)

  

 M1

4(26.7%)

8(24.2%)

  

ER Status

  

2.334

0.127

 Positive

7(46.7%)

23(69.7%)

  

 Negative

8(53.3%)

10(30.3%)

  

PR Status

  

3.499

0.061

 Positive

3(20.0%)

16(48.5%)

  

 Negative

12(80.0%)

17(51.5%)

  

HER2 Status

  

0.162

0.688

 Positive

5(33.3%)

13(39.4%)

  

 Negative

10(66.7%)

20(60.6%)

  

Molecular Subtype

  

3.232

0.337

 HR+/HER2-

6(40.0%)

15(45.5%)

  

 HR+/HER2+

1(6.7%)

8(24.2%)

  

 HER2+

4(26.7%)

5(15.2%)

  

 TNBC

4(26.7%)

5(15.2%)

  

Ki-67

  

0.041

0.839

 <30%

5(33.3%)

12(36.4%)

  

 ≥30%

10(66.7%)

21(63.6%)

  

SUVmax

8.38 ± 6.61

7.70 ± 4.49

0.416

0.679

SUVmean

2.66 ± 2.02

2,94 ± 1.91

-0.477

0.636

TLG*

62.00(19.11 ~ 126.26)

44.26(15.62 ~ 129.46)

-0.612

0.541

MTV*

35.50(20.83 ~ 64.00)

17.70

(8.70 ~ 47.53)

-2.146

0.032

  1. *Those data are described as median (lower quartile ~ upper quartile) and tested by the Mann-Whitney U test. AR-, androgen receptor negative; AR+, androgen receptor positive; t: independent t-test; x2, Chi-square test; z, Mann-Whitney U test; BMI: body mass index; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor-2; IDC, invasive ductal breast carcinoma; HR, hormone receptor (included ER and/or PR); TNBC, triple-negative breast cancer; Ki-67, cellular proliferation index; SUVmax, maximum standardized uptake value; SUVmean, mean standardized uptake value; TLG, total lesion glycolysis; MTV, metabolic tumor volume