Effect of cerebrospinal fluid area mask correction on 123I-FP-CIT SPECT images in idiopathic normal pressure hydrocephalus

Ohba, Makoto; Kobayashi, Ryota; Iseki, Chifumi; Kirii, Kazukuni; Morioka, Daichi; Otani, Koichi; Ohta, Yasuyuki; Sonoda, Yukihiko; Suzuki, Koji; Kanoto, Masafumi

doi:10.1186/s12880-023-01038-x

Table 1 Demographic/clinical data and SBRs before and after CSF area mask correction

From: Effect of cerebrospinal fluid area mask correction on ¹²³I-FP-CIT SPECT images in idiopathic normal pressure hydrocephalus

	Case	Age	Diagnosis	Evans index	Visual assessment	Removed Striatal VOI (pixels)	Removed BG VOI (pixels)	Differences in VOIs (Removed Striatal VOI-Removed BG VOI) (pixels)	ncSBR	cSBR	SBR　change
Decreased　SBR group	1	66	definite iNPH	0.46	Abnormal	1572	3059	-1487.0	5.03	4.87	0.15
	2	70	definite iNPH	0.32	Normal	1182	1947	-765.0	6.21	5.58	0.63
	3	71	definite iNPH	0.30	Normal	1712	2226	-514.0	5.12	4.87	0.26
	4	72	definite iNPH	0.35	Abnormal	946	2475	-1529.0	8.66	7.67	0.99
	5	73	definite iNPH	0.33	Normal	1025	2221	-1196.0	7.07	6.13	0.94
	6	77	definite iNPH	0.31	Normal	1314	2210	-896.0	6.58	6.08	0.50
	7	78	definite iNPH	0.31	Normal	1345	2122	-777.0	7.25	6.67	0.58
	8	81	definite iNPH	0.30	Normal	1372	1435	-63.0	5.77	5.51	0.26
	9	79	definite iNPH	0.31	Normal	1290	1813	-523.0	6.13	5.64	0.49
	10	79	definite iNPH	0.33	Normal	1733	1854	-121.0	6.52	6.48	0.04
	11	80	definite iNPH	0.30	Normal	1474	1739	-265.0	5.70	5.64	0.06
	12	81	definite iNPH	0.34	Normal	1636	2057	-421.0	5.51	4.96	0.54
	13	84	definite iNPH	0.35	Normal	1118	2376	-1258.0	6.07	5.27	0.81
	14	72	probable iNPH	0.35	Abnormal	1445	2384	-939.0	3.41	3.40	0.01
	15	75	probable iNPH	0.41	Normal	1931	2253	-322.0	8.46	7.78	0.68
	16	76	probable iNPH	0.31	Normal	1148	2645	-1497.0	6.68	5.66	1.02
	17	80	probable iNPH	0.35	Normal	1202	2042	-840.0	4.79	4.45	0.33
	18	83	probable iNPH	0.30	Abnormal	1410	2412	-1002.0	5.79	5.18	0.60
	19	78	possible iNPH	0.31	Normal	1304	2029	-725.0	6.04	5.80	0.24
	20	84	possible iNPH	0.30	Normal	1547	1852	-305.0	4.55	4.35	0.19
Increased SBR group	21	78	definite iNPH	0.38	Normal	2056	1763	293.0	4.45	4.87	-0.41
	22	83	definite iNPH	0.34	Normal	1933	1828	105.0	4.88	5.03	-0.14
	23	86	probable iNPH	0.36	Abnormal	1916	1426	490.0	2.41	2.88	-0.47
	24	80	possible iNPH	0.32	Abnormal	2197	1394	803.0	2.12	2.61	-0.49
	25	83	possible iNPH	0.41	Abnormal	2076	2140	-64.0	2.08	2.20	-0.12
Average (± SD)		78.0 ± 4.9	-	-	-	1515.4 ± 350.8	2068.1 ± 387.6	-	5.49 ± 1.71	5.18 ± 1.38	-

SBR Specific binding ratio, CSF Cerebrospinal fluid, F Female, M Male, iNPH idiopathic normal pressure hydrocephalus, VOI Volume of interest, BG Background, ncSBR the SBR without CSF area mask correction, cSBR the SBR with CSF area mask correction, SD Standard deviation, SBR change: the difference in SBR before and after CSF area mask correction, Removed Striatal VOI: volume of the striatal VOI removed by CSF area mask correction, Removed BG VOI: volume of the BG VOI removed by CSF area mask correction, Differences in VOIs: The volume difference in VOIs removed by CSF area mask correction

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ISSN: 1471-2342

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