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Table 2 Comparison of contrast ratio values of N1, N2, volume-weighted mean of N1 and N2, and whole SNpc in IPD patients and healthy control subjects

From: Diagnostic performance of a high-spatial-resolution voxelwise analysis of neuromelanin-sensitive imaging in early-stage idiopathic Parkinson’s disease

 

Contrast Ratio Values‡

p value§

 

IPD (n = 50)

Healthy Control (n = 50)

Right N1

0.149459 ± 0.038455

0.194505 ± 0.037177

< 0.001*

Left N1

0.133328 ± 0.032071

0.169160 ± 0.031976

< 0.001*

Right N2

0.230245 ± 0.046347

0.278181 ± 0.047634

< 0.001*

Left N2

0.235784 ± 0.043828

0.314169 ± 0.048772

< 0.001*

Right N1 + N2

0.153235 (0.123855–0.179959)

0.267800 (0.243768–0.303305)

< 0.001†

Left N1 + N2

0.140459 (0.118907–0.159236)

0.267800 (0.242878–0.303305)

< 0.001†

Right whole SNpc

0.131397 ± 0.026681

0.141422 ± 0.024871

< 0.001*

Left whole SNpc

0.127099 ± 0.024357

0.137873 ± 0.024597

< 0.001*

  1. Note. IPD, idiopathic Parkinson’s disease; N1, the region of interest in the presumed nigrosome 1 region; N2, the region of interest in the presumed nigrosome 2 region; N1 + N2, volume-weighted mean of N1 and N2; SNpc, the substantia nigra pars compacta
  2. * Independent sample t-test
  3. † Mann-Whitney U test
  4. ‡ Contrast ratio values are presented as the mean ± standard deviation, except for the right and left N1 + N2, which are presented as the median (interquartile range)
  5. § Adjusted by Bonferroni correction
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BMC Medical Imaging

ISSN: 1471-2342

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