High-temporal resolution DCE-MRI improves assessment of intra- and peri-breast lesions categorized as BI-RADS 4

BMC Medical Imaging

Table 2 Pharmacokinetic parameters between benign and malignant lesions

Pharmacokinetic parameters	Lesion area			Peri area			BPE area
Pharmacokinetic parameters	Benign	Malignant	P	Benign	Malignant	P	Benign	Malignant	P
High-temporal-resolution DCE-MRI group
K^trans	0.167 ± 0.156	0.416 ± 0.189	0.000*	0.085 ± 0.068	0.140 ± 0.073	0.002*	0.060 ± 0.070	0.044 ± 0.047	0.471
K_ep	0.418 ± 0.177	0.943 ± 0.345	0.000*	0.271 ± 0.121	0.412 ± 0.143	0.000*	0.263 ± 0.192	0.254 ± 0.158	0.983
V_e	0.371 ± 0.233	0.449 ± 0.119	0.013*	0.284 ± 0.154	0.335 ± 0.143	0.378	0.204 ± 0.123	0.189 ± 0.170	0.355
V_p	0.005 ± 0.009	0.022 ± 0.020	0.000*	0.007 ± 0.010	0.020 ± 0.015	0.000*	0.003 ± 0.003	0.004 ± 0.006	0.988
Low-temporal-resolution DCE-MRI group
K^trans	2.311 ± 1.539	1.830 ± 1.185	0.141	1.916 ± 1.256	1.588 ± 0.858	0.452	2.764 ± 1.633	1.699 ± 1.141	0.005*
K_ep	0.219 ± 0.203	0.415 ± 0.194	0.000*	0.235 ± 0.156	0.304 ± 0.169	0.081	0.304 ± 0.304	0.340 ± 0.198	0.164
Ve	0.454 ± 0.213	0.558 ± 0.188	0.052	0.309 ± 0.114	0.349 ± 0.117	0.120	0.585 ± 0.288	0.475 ± 0.177	0.059
V_p	0.720 ± 0.280	0.642 ± 0.221	0.070	0.566 ± 0.217	0.403 ± 0.157	0.001*	0.663 ± 0.298	0.457 ± 0.196	0.002*

ISSN: 1471-2342