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Fig. 1 | BMC Medical Imaging

Fig. 1

From: Sclerosing angiomatoid nodular transformation of the spleen: multimodality imaging features and literature review

Fig. 1

An elderly woman with a history of anemia. Microscopically, the splenic lesion consisted of variably sized nodules surrounded by variable fibrous bands (H&E, original magnification×200). There was proliferation of both collagen fiber (B) and multiple micro-vessels, with inflammatory cell infiltration(1 A). Unenhanced axial CT image (1B) shows a hypodense lesion in spleen. The lesion shows heterogeneous enhancement on arterial phase(1 C) and portal phase(1D). T2-weighted images(1E) and DWI(1 F) show a hypointensity lesion with more hypointense scars in the center. After contrast administration, the lesion shows less contrast-enhanced than the spleen parenchyma in arterial phase(1G) and portal venous phase(1 H). The lesion shows continued progressive enhancement on delayed phase(1I)

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