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Table 1 Basic information of NSCLC patients for model construction and model validation

From: The value on SUV-derived parameters assessed on 18F-FDG PET/CT for predicting mediastinal lymph node metastasis in non-small cell lung cancer

Characteristics

Model construction

(N = 224)

Model validation

(N = 100)

Value

p value

Age

63.48 ± 9.57

63.33 ± 9.54

− 0.128a

0.898

Gender

  

0.692b

0.406

Male

137

66

  

Female

87

34

  

Smoking history

  

0.481b

0.488

No

128

53

  

Yes

96

47

  

SUVmax of mediastinal lymph node

1.87 (1.41, 3.29)

2.03 (1.41, 3.76)

11,625.00d

0.585

Primary-tumor SUVmax

7.13 (3.05, 11.28)c

7.46 (2.78, 11.91)

11,572.50d

0.632

Primary-tumor SUVpeak

4.48 (2.11, 7.33)c

5.14 (2.00, 8.31)

11,546.00d

0.657

Primary-tumor SUVmean

4.20 (1.78, 6.82)c

4.35 (1.57, 7.15)

11,528.00d

0.647

Primary-tumor MTV

16.51 (9.14, 35.75)c

15.73 (9.14, 37.65)

11,164.50d

0.964

Primary-tumor TLG

53.99 (19.15, 228.81)c

57.43 (19.65, 244.25)

11,313.00d

0.885

Primary tumor size (mm)

28.00 (20.00, 40.00)c

27.50 (20.00, 38.00)

11,350.00d

0.847

CEA

3.24 (1.95, 5.63)c

3.07 (1.98, 5.12)

10,935.00d

0.734

CYFRA21-1

2.83 (2.10, 4.14)c

2.66 (2.07, 3.96)

10,731.50d

0.547

CA19-9

11.22 (8.21, 17.30)c

10.47 (7.26, 17.26)

10,465.00d

0.345

SCC

0.93 (0.70, 1.40)c

1.00 (0.73, 1.40)

11,502.50d

0.697

NSE

13.05 (11.31, 15.63)c

12.89 (10.79, 15.60)

10,691.50d

0.514

TPA

87.56 (63.19, 134.98)c

82.26 (63.15, 129.53)

10,948.50d

0.747

proGRP

43.55 (34.30, 54.16)c

44.87 (35.64, 55.24)

11,837.50d

0.413

EGFR mutation

  

0.589b

0.443

No

166

70

  

Yes

58

30

  

ALK rearrangement

  

0.238b

0.626

No

205

95

  

Yes

14

5

  
  1. NSCLC, non-small cell lung cancer; SUV, standardized uptake value; SUVmax, maximum SUV; SUVpeak, peak of SUV; SUVmean, average of SUV; MTV, metabolic tumor volume; TLG, total lesion glycolysis; FDG, fluorodeoxyglucose; CEA, carcinoembryonic antigen; CYFRA21-1, cytokeratin 19 fragment; CA19-9, carbohydrate antigen 19–9; SCC, squamous cell carcinoma antigen; NSE, neuron-specific enolase; TPA, tissue polypeptide antigen; proGRP, precursor of gastrin releasing peptide; EGFR, epidermal growth factor receptor; ALK, anaplastic lymphoma kinase
  2. aT test. bPearson Chi-Square test. cMedian [Q1, Q1)]. dMann-Whiteney test