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Table 1 Baseline characteristics of patients with WD

From: Application of attenuation coefficient in the assessment of hepatic involvement in children and adolescents with Wilson’s disease

Parameter

All

Group 1

Group 2

Group 3

P*

Number (N)

62

25

19

18

Age (Year)

14.00 (5.00)

15.00 (4.50)

12.00 (6.00)

12.50 (5.25)

0.035

Male (N)

37

17

12

8

0.279

CP (g/l)

0.019 (0.022)

0.018 (0.026)

0.017 (0.018)

0.024 (0.024)

0.915

24 h urinary Cu-before (µg/24 h)

738.63 (513.47)

758.67 (480.58)

708.98 (460.43)

714.88 (715.17)

0.917

24 h urinary Cu-after (µg/24 h)

807.53 (503.56)

839.79 (426.14)

788.26 (1053.55)

777.24 (599.79)

0.198

CIV (ng/ml)

62.98 (31.29)

49.31 (32.18)

68.07 (21.01)

78.10 (68.90)

0.002

HA (ng/ml)

87.63 (63.30)

63.04 (24.04)

90.34 (41.77)

156.04 (91.67)

< 0.001

LN (ng/ml)

132.02 (95.84)

89.68 (49.80)

165.26 (59.20)

213.10 (92.36)

< 0.001

PIIINP (ng/ml)

34.40 (23.01)

30.82 (20.16)

30.01 (17.13)

45.91 (35.69)

0.008

PLT (×109)

243.46 (119.00)

229.00 (81.00)

284.00 (111.00)

218.50 (155.00)

0.360

ALT (U/L)

49.90 (35.15)

49.30 (26.05)

68.60 (59.60)

36.40 (28.38)

0.008

AST (U/L)

34.35 (19.17)

28.00 (20.15)

37.60 (15.40)

33.35 (19.85)

0.036

TG (mmol/L)

1.32 (1.06)

1.26 (0.76)

1.46 (1.35)

1.51 (1.31)

0.648

Internal diameter of the portal vein (mm)

10.00 (2.10)

10.00 (3.00)

9.70 (2.50)

9.75 (1.50)

0.383

Velocity of the blood flow of the portal vein (cm/s)

19.90 (6.10)

20.70 (5.15)

20.10 (6.40)

18.50 (5.40)

0.383

  1. Quantitative data were expressed with median (IQR)
  2. *Kruskal–Wallis test or chi-squre test