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Table 2 Variables in IPH and HBV-infected patients without or with high-risk varices

From: Performance of spleen stiffness measurement by 2D-shear wave elastography in evaluating the presence of high-risk varices: comparative analysis of idiopathic portal hypertension versus hepatitis B virus

Variables

Non-HRV

HRV

HBV(n = 55)

IPH(n = 56)

P values

HBV(n = 47)

IPH(n = 30)

P values

Age (year)

49.7 ± 10.7

47.9 ± 10.8

0.386

51.1 ± 11.6

46.8 ± 14.6

0.152

No. of male

34 (61.8%)

29 (51.8%)

0.288

34 (72.3%)

16 (53.3%)

0.090

2D-SWE (kPa)

      

 LS

15.3 (12.5–16.7)

8.9 (6.2–10.1)

 < 0.0001

18.3 (14.4–21.6)

11.1 (9.6–12.2)

 < 0.0001

 SS

26.0 (24.4–34.0)

33.8 (28.5–36.9)

 < 0.0001

42.9 (39.2–47.0)

50.2 (45.6–54.3)

 < 0.0001

Conventional US

      

 Spleen size (cm)

      

  Thickness

4.0 ± 1.0

5.0 ± 1.0

0.012

5.6 ± 0.9

5.5 ± 0.7

0.758

  Diameters

14.1 ± 3.1

14.5 ± 2.0

0.452

20.8 ± 2.7

18.5 ± 3.9

0.004

 PVF (ml/min)

1371.0 (728.5–2102.5)

1871.0 (1037.5–3460.5)

0.188

1904.0 (1570.5–2983.5)

2115.0 (1207.8–2915.3)

0.757

 SVF (ml/min)

966.0 (444.0–2384.5)

833.0 (373.0–1839.5)

0.235

1072.0 (701.5–2086.5)

1224.5 (699.0–1848.8)

0.995

Laboratory values

      

 ALT (IU/L)

23.0 (11.5–61.0)

20.0 (18.5–31.0)

0.002

25.0 (18.0–32.0)

21.0 (14.5–26.0)

0.067

 ALB (g/L)

37.3 (30.0–43.3)

39.1 (36.8–42.6)

0.001

35.0 (31.8–39.8)

39.3 (33.0–44.7)

0.050

 AST (IU/L)

28.0 (23.0–46.5)

26.0 (20.0–34.0)

 < 0.0001

31.0 (22.0–37.0)

23.0 (19.8–28.0)

0.015

 TBIL (µmol/L)

24.1 (16.2–37.3)

20.6 (16.0–23.1)

0.391

20.0 (13.6–30.3)

16.1 (12.7–23.9)

0.222

 DBIL (µmol/L)

8.9 (7.7–11.1)

7.8 (6.8–9.6)

 < 0.0001

10.3 (7–16.1)

6.5 (5.6–9.3)

0.010

 IBIL (µmol/L)

19.1 (8.1–24.3)

11.3 (10.6–14.8)

 < 0.0001

10.6 (6.5–16.1)

9.9 (6.6–14.3)

0.620

 ALP (IU/L)

75.0 (56.5–102.5)

87.0 (58.5–106.5)

0.438

80.0 (61.0–102.0)

75.0 (57.5–112.0)

0.548

 GGT (IU/L)

46.0 (26.5–53.0)

44.0 (22.0–90.0)

0.824

32.0 (19.0–64.0)

30.5 (22.8–53.0)

0.975

 PLT (109/µl)

44.0 (25.0–90.5)

81.0 (62.0–87.0)

 < 0.0001

53.0 (36.0–75.0)

52.5 (38.8–77.0)

0.967

 PT (s)

17.3 (16.3–17.9)

13.4 (12.8–14.9)

 < 0.0001

16.7 (15.5–18.8)

15.1 (13.5–15.5)

 < 0.0001

  1. Continuous variables were expressed as means ± standard deviations (SD) or medians [interquartile ranges (IQR)], and categorical variables were expressed as n(%), when appropriate
  2. HBV, hepatitis B virus; IPH, idiopathic portal hypertension; GEV, gastroesophageal varices; Non-HRV, without high-risk varices; HRV, high-risk varices; LS, liver stiffness; SS, spleen stiffness; 2D-SWE, two-dimensional shear-wave elastography; PVF, portal venous flow volume; SVF, splenic venous; ALT, alanine aminotransferase; ALB, albumin; AST, aspartate aminotransferase; TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; ALP, alkaline phosphatase; GGT, glutamyl transpeptidase; PLT, platelet count; PT, prothrombin time
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BMC Medical Imaging

ISSN: 1471-2342

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