Table 2 Mann–Whitney U test for differences in groups

Pretreatment parameters	CB (n = 10) [median (IQR)]	NCB (n = 21) [median (IQR)]	P value
SUV_max	5.36 (4.26, 10.20)	12.50 (8.26, 15.78)	0.004*
SUV_mean	2.03 (1.55, 4.20)	3.87 (2.50, 5.35)	0.043*
SUV_peak	3.45 (2.41, 9.73)	8.59 (6.38, 12.74)	0.017*
MTV	3.65 (1.78, 9.52)	11.65 (5.51, 32.00)	0.065
TLG	8.89 (3.42, 49.74)	47.01 (23.90, 422.73)	0.053
SUV_maxwb	51.57 (4.73, 82.69)	112.50 (30.26, 302.32)	0.031*
SUV_meanwb	24.48 (2.25, 49.72)	65.68 (14.80, 157.55)	0.043*
SUV_peakwb	37.42 (3.09, 58.21)	85.76 (23.18, 216.98)	0.053
MTV_wb	29.21 (2.37, 145.26)	111.14 (21.79, 531.84)	0.035*
TLG_wb	61.15 (4.99, 303.46)	263.86 (64.24, 1644.70)	0.035*
LDH, U/L	226.00 (186.00, 240.50)	322.00 (275.00, 359.50)	0.001*
Absolute platelet count, × 10⁹/L	248.00 (187.25, 275.00)	188.00 (141.00, 308.50)	0.393
Absolute neutrophil count, × 10⁹/L	4.22 (3.04, 5.27)	3.87 (2.14, 4.84)	0.693
Albumin levels, g/L	45.67 (42.25, 49.02)	44.00 (38.15, 51.90)	0.852
dNLR	2.59 (1.87, 3.71)	1.78 (1.09, 3.27)	0.186

CB Clinical Benefit; NCB no-Clinical Benefit; IQR interquartile range; SUV_max maximum standardized uptake value; SUV_mean mean standardized uptake value; SUV_peak peak standardized uptake value; MTV metabolic tumor volume; TLG total lesion glycolysis; SUV_maxwb whole-body maximum standardized uptake value; SUV_meanwb whole-body mean standardized uptake value; SUV_peakwb whole-body peak standardized uptake value; MTV_wb whole-body metabolic tumor volume; TLG_wb whole-body total lesion glycolysis; LDH lactate dehydrogenase; dNLR derived neutrophil-to-lymphocyte ratio, defined as absolute neutrophil count/[white blood cell concentration − absolute neutrophil count];*P < 0.05

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