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Table 1 CEUS characteristics of benign and malignant thyroid nodules

From: Value of CEUS features in diagnosing thyroid nodules with halo sign on B-mode ultrasound

Indicator

Pathology

p

Benign

Malignant

 

Wash-in

  

0.216*

 Earlier

7 (16.3%)

1 (3.2%)

 

 Meantime

30 (69.8%)

24 (77.4%)

 

 Later

6 (14.0%)

6 (19.4%)

 

Intensity

  

0.016*

 Hypo-enhancement

2 (4.7%)

9 (29.0%)

0.013#

 Iso-enhancement

27 (62.8%)

14 (45.2%)

0.86#

 Hyper-enhancement

14 (32.6%)

8 (25.8%)

0.014#

Homogeneity

  

0.212*

 Homogeneity

40 (93.0%)

25 (80.6%)

 

 Heterogeneity

3 (7.0%)

6 (19.4%)

 

Enhanced defect

  

0.052*

 Without

29 (67.4%)

27 (87.1%)

 

 With

14 (32.6%)

4 (12.9%)

 

Enhanced pattern

  

0.699*

Entire

40 (93.0%)

27 (87.1%)

 

 Centripetal

1 (2.3%)

2 (6.5%)

 

 Eccentrical

2 (4.7%)

2 (6.5%)

 

Enhancing ring

  

0.001*

 Without

18 (41.9%)

14 (45.2%)

0.008#

 High

11 (25.6%)

0 (0.0%)

0.001#

 Low

14 (32.6%)

17 (54.8%)

0.454#

Wash out

  

0.801*

 Earlier

10 (23.3%)

8 (25.8%)

 

 Later

33 (76.7%)

23 (74.2%)

 
  1. *Determined with the χ2 test
  2. #Bonferroni correction was used for comparisons of the three categories, and values of p < 0.017 (0.05/3) were considered statistically significant for the pairwise comparisons