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Fig. 4 | BMC Medical Imaging

Fig. 4

From: Amide proton transfer MRI differentiates between progressive multifocal leukoencephalopathy and malignant brain tumors: a pilot study

Fig. 4

MRI from a 73-year-old man with GBM. a T2-weighted sequence, axial section, shows well-defined GBM with high SI in the body of the corpus callosum (white arrow). b T1-weighted sequence, axial section, shows well-defined GBM with low SI in the body of the corpus callosum (white arrow). c 3D contrast-enhanced T1 sequence, axial section, shows enhancement with a poor enhancement area in GBM (white arrow). d 3D ASL sequence, axial section, shows slightly high SI in GBM. e APT scout image, axial section, shows the ROI placed in the GBM avoiding the poor enhancement area that may represent a necrotic portion. f APT scout image, axial section, shows the ROI placed in normal-appearing tissue in right frontal lobe. g APT imaging shows high SI in GBM (white arrow). GBM glioblastoma multiforme, SI signal intensity, ASL arterial spin labelling, APT amide proton transfer

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