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Table 3 Strain parameters and tissue characteristics in different groups

From: Diastolic dysfunction assessed by cardiac magnetic resonance imaging tissue tracking on normal-thickness wall segments in hypertrophic cardiomyopathy

 

Control (n = 480)

Group A (n = 716)

Group B (n = 111)

Group C (n = 181)

p-value

Strain parameters

Radial PS (%)

37.30 (29.00, 48.19)

36.64 (28.58,47.58)

29.04 (22.34, 36.86)*#

25.51 (18.02, 33.02)*#

 < 0.001

Circumferential PS (%)

− 20.83 (− 23.80, − 17.71)

− 20.53 (− 23.73, − 17.56)

− 17.90 (− 20.66, − 15.04)*#

− 16.46 (− 19.06, − 12.69)*#

 < 0.001

Longitudinal PS (%)

− 15.70 (− 20.78, − 10.62)

− 15.68 (− 20.56, − 9.64)

− 13.73 (− 17.23, − 8.66)*#

− 10.63 (− 14.83, − 6.58)*#

 < 0.001

Radial systolic PSR (1/s)

2.06 (1.58, 2.81)

2.28 (1.69, 3.00)*

1.75 (1.37, 2.32)*#

1.51 (1.14, 2.03)*#

 < 0.001

Circumferential systolic PSR (1/s)

− 1.18 (− 1.50, − 0.99)

− 1.28 (− 1.55, − 1.02)

− 1.14 (− 1.41, − 0.94) #

− 1.02 (− 1.27, − 0.83)*#$

 < 0.001

Longitudinal systolic PSR (1/s)

− 1.10 (− 1.49, − 0.76)

− 1.14 (− 1.53, − 0.71)

− 1.02 (− 1.42, − 0.63)

− 0.93 (− 1.23, − 0.61)*#

 < 0.001

Radial diastolic PSR (1/s)

− 2.67 (− 3.58, − 1.96)

− 2.43 (− 3.36, − 1.78)*

− 1.71 (− 2.27, − 1.24)*#

− 1.38 (− 1.94, − 1.02)*#

 < 0.001

Circumferential diastolic PSR (1/s)

1.39 (1.14, 1.78)

1.28 (1.01,1.60)*

1.00 (0.80, 1.20)*#

0.90 (0.73, 1.10)*#

 < 0.001

Longitudinal diastolic PSR (1/s)

1.28 (0.90, 1.71)

1.16 (0.75,1.51)*

0.96 (0.67, 1.23)*#

0.88 (0.60, 1.21)*#

 < 0.001

Tissue characteristics

LGE, n (%)

0 (0)

30 (4.1)*

14 (12.6)*#

62 (34.2)*#$

 < 0.001

Mean native T1 (ms)

1231.2 (1194.7, 1264.2)

1252.2 (1222.8, 1287.7)*

1278.7 (1244.8, 1305.2)*#

1293.1 (1268.7, 1332.4)*#$

 < 0.001

Mean T2 (ms)

39.8 (37.9, 41.9)

39.8 (38.4, 41.4)

39.4 (38.1, 41.2)

39.9 (38.7, 41.3)

0.59

Mean ECV (%)

25.0 (22.9, 27.0)

25.2 (22.8, 27.7)

25.5 (23.3, 29.4)

26.6 (23.9, 29.7)*#

 < 0.001

  1. The groups (A, B, C) of HCM are divided according to the maximum thickness of the segmental myocardium: Group A, < 12 mm; Group B, 12-15 mm; Group C, > 15 mm. Analysis of the segments is based on the 16-segment AHA model
  2. The values are presented as frequencies (percentages) or median (interquartile range). Bold values indicate p < 0.05 when compared among the four groups
  3. *, vs. control, p < 0.05;
  4. #, vs. Group A, p < 0.05;
  5. $, vs. Group B, p < 0.05
  6. PS, peak strain; PSR, peak strain rate; LGE, late gadolinium enhancement; ECV, extracellular volume; HCM, hypertrophic cardiomyopathy, AHA, American Heart Association