Evaluating renal iron overload in diabetes mellitus by blood oxygen level-dependent magnetic resonance imaging: a longitudinal experimental study

Table 4 MCR values in the control, iron overload, diabetes, and diabetes with iron overload groups at different time points

Time	Group C (n = 10)	Group I (n = 10)	Group D (n = 10)	Group DI (n = 10)	P (groups)	P (C-I)	P (C-D)	P (C-DI)	P (I-D)	P (I-DI)	P (D-DI)
week 0	1.29 ± 0.10	1.31 ± 0.07	1.33 ± 0.06	1.34 ± 0.05	0.488	0.515	0.254	0.149	0.619	0.420	0.756
week 4	1.35 ± 0.05	1.01 ± 0.06	1.15 ± 0.11	1.07 ± 0.11	< 0.001^#	< 0.001^#	< 0.001^#	< 0.001^#	0.001^#	0.172	0.029^#
week 8	1.35 ± 0.05	1.04 ± 0.08	1.18 ± 0.05	1.01 ± 0.13	< 0.001^#	< 0.001^#	< 0.001^#	< 0.001^#	0.001^#	0.453	< 0.001^#
week 12	1.37 ± 0.06	1.14 ± 0.14	1.13 ± 0.08	1.02 ± 0.11	< 0.001^#	< 0.001^#	< 0.001^#	< 0.001^#	0.965	0.019^#	0.021^#
P (time_points)	0.088	< 0.001^#	< 0.001^#	< 0.001^#
P (w0–w4)	0.088	< 0.001^#	< 0.001^#	< 0.001^#
P (w0–w8)	0.078	< 0.001^#	< 0.001^#	< 0.001^#
P (w0–w12)	0.037^#	< 0.001^#	< 0.001^#	< 0.001^#
P (w4–w8)	0.977	0.499	0.535	0.102
P (w4–w12)	0.686	0.011^#	0.670	0.362
P (w8–w12)	0.694	0.034^#	0.361	0.727

Data was represented as mean ± standard deviation
C Control, I Iron overload, D Diabetes, DI Diabetes with iron overload
^#P < 0.05 denotes the difference is statistically significant; P (groups)-values among groups C, I, D, and DI; P (C-I)-values between groups C and I; P (C-D)-values between groups C and D; P (C-DI)-values between groups C and DI; P (I-D)-values between the I and D groups; P (I-DI)-values between the I and DI groups; P (D-DI)-values between the D and DI groups; P (time_points) -values among week 0, 4, 8, and 12; P (w0–w4)-values between week 0 and 4; P (w0–w8)-values between week 0 and 8; P (w0–w12)-values between week 0 and 12; P (w4–w8)-values between week 4 and 8; P (w4–w12)-values between week 4 and 12; and P (w8–w12)-values between week 8 and 12

ISSN: 1471-2342