Evaluating renal iron overload in diabetes mellitus by blood oxygen level-dependent magnetic resonance imaging: a longitudinal experimental study

Table 3 MR₂^* values in the control, iron overload, diabetes, and diabetes with iron overload groups at different time points

Time	Group C (n = 10)	Group I (n = 10)	Group D (n = 10)	Group DI (n = 10)	P (groups)	P (C-I)	P (C-D)	P (C-DI)	P (I-D)	P (I-DI)	P (D-DI)
week 0	28.86 ± 1.59	29.53 ± 1.95	29.28 ± 2.54	30.41 ± 2.08	0.403	0.472	0.655	0.103	0.784	0.349	0.229
week 4	29.86 ± 1.40	30.41 ± 1.97	30.73 ± 2.89	31.78 ± 2.33	0.276	0.582	0.382	0.060	0.743	0.173	0.296
week 8	29.53 ± 0.89	31.60 ± 1.53	31.33 ± 1.97	32.81 ± 1.90	0.001^#	0.007^#	0.019^#	< 0.001^#	0.704	0.107	0.049^#
week 12	29.29 ± 1.87	34.19 ± 5.14	31.88 ± 2.50	36.47 ± 5.95	0.004^#	0.014^#	0.180	0.001^#	0.229	0.236	0.020^#
P (time_points)	0.738	0.006^#	0.068	< 0.001^#
P (w0–w4)	0.270	0.332	0.110	0.131
P (w0–w8)	0.450	0.024^#	0.026^#	0.010^#
P (w0–w12)	0.742	0.001^#	0.054	< 0.001^#
P (w4–w8)	0.709	0.171	0.494	0.238
P (w4–w12)	0.715	0.018^#	0.455	0.004^#
P (w8–w12)	0.870	0.082	0.703	0.016^#

Data was represented as mean R₂^* value (s⁻¹) ± standard deviation
C Control, I Iron overload, D Diabetes, DI Diabetes with iron overload
^#P < 0.05 denotes the difference is statistically significant; P (groups)-values among groups C, I, D, and DI; P (C-I)-values between groups C and I; P (C-D)-values between groups C and D; P (C-DI)-values between groups C and DI; P (I-D)-values between the I and D groups; P (I-DI)-values between the I and DI groups; P (D-DI)-values between the D and DI groups; P (time_points) -values among week 0, 4, 8, and 12; P (w0–w4)-values between week 0 and 4; P (w0–w8)-values between week 0 and 8; P (w0–w12)-values between week 0 and 12; P (w4–w8)-values between week 4 and 8; P (w4–w12)-values between week 4 and 12; and P (w8–w12)-values between week 8 and 12

ISSN: 1471-2342