Evaluating renal iron overload in diabetes mellitus by blood oxygen level-dependent magnetic resonance imaging: a longitudinal experimental study

Table 2 CR₂^* values in the control, iron overload, diabetes, and diabetes with iron overload groups at different time points

Time	Group C (n = 10)	Group I (n = 10)	Group D (n = 10)	Group DI (n = 10)	P (groups)	P (C-I)	P (C-D)	P (C-DI)	P (I-D)	P (I-DI)	P (D-DI)
week 0	22.46 ± 1.94	22.51 ± 0.82	22.06 ± 1.41	22.73 ± 1.18	0.757	0.938	0.528	0.671	0.478	0.728	0.293
week 4	22.09 ± 0.97	30.26 ± 2.99	26.74 ± 1.65	30.07 ± 3.03	< 0.001^#	< 0.001^#	< 0.001^#	< 0.001^#	0.002^#	0.855	0.003^#
week 8	21.88 ± 0.83	30.67 ± 2.37	26.66 ± 1.24	33.10 ± 4.39	< 0.001^#	< 0.001^#	< 0.001^#	< 0.001^#	0.001^#	0.044^#	< 0.001^#
week 12	21.38 ± 1.40	30.4 ± 5.65	28.25 ± 2.83	36.06 ± 6.76	< 0.001^#	< 0.001^#	0.002^#	< 0.001^#	0.292	0.012^#	0.001^#
P (time_points)	0.750	< 0.001^#	< 0.001^#	< 0.001^#
P (w0–w4)	0.625	< 0.001^#	< 0.001^#	< 0.001^#
P (w0–w8)	0.509	< 0.001^#	< 0.001^#	< 0.001^#
P (w0–w12)	0.486	< 0.001^#	< 0.001^#	< 0.001^#
P (w4–w8)	0.816	0.654	0.930	0.002^#
P (w4–w12)	0.699	0.900	0.409	0.002^#
P (w8–w12)	0.797	0.927	0.412	0.130

Data was represented as mean R₂^* value (s⁻¹) ± standard deviation
C Control, I Iron overload, D Diabetes, DI Diabetes with iron overload
^#P < 0.05 denotes the difference is statistically significant; P (groups)-values among groups C, I, D, and DI; P (C-I)-values between groups C and I; P (C-D)-values between groups C and D; P (C-DI)-values between groups C and DI; P (I-D)-values between the I and D groups; P (I-DI)-values between the I and DI groups; P (D-DI)-values between the D and DI groups; P (time_points) -values among week 0, 4, 8, and 12; P (w0–w4)-values between week 0 and 4; P (w0–w8)-values between week 0 and 8; P (w0–w12)-values between week 0 and 12; P (w4–w8)-values between week 4 and 8; P (w4–w12)-values between week 4 and 12; and P (w8–w12)-values between week 8 and 12

ISSN: 1471-2342