Fig. 6

Prussian blue staining images (× 200) of the left kidneys in the C, I, D, and DI groups at week 0, 4, 8, and 12. There were no blue stained granules in the C group from week 0–12 and the I, D, and DI groups at week 0. In the I group, there were few blue stained granules in the glomeruli since week 4. A small amount of blue stained granules was observed in proximal tubule cells of renal cortex at week 12. In the D group, blue stained granules were present in the proximal tubule cells in the renal cortex since week 4. In the DI group, there were several blue stained granules in both glomeruli and proximal tubule cells since week 4. Furthermore, the amount of the granules increased significantly in both glomeruli and proximal tubule cells and was more than those in the I and D groups at week 12.