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Table 3 Rates of predictive characteristics of OFCs by prenatal US and fetal MRI

From: Comparison of prenatal ultrasound with MRI in the evaluation and prediction of fetal orofacial clefts

Characteristics

CLO

CLP

CPO

Total

US

MRI

P value

US

MRI

P value

US

MRI

P value

US

MRI

P value

TPR (%)

22/73 (30.14)

11/12 (91.67)

< 0.001

205/215 (95.35)

30/31 (96.77)

0.916

3/46 (6.52) 

3/7 (42.86)

0.029

230/281 (81.85)

44/49 (89.80)

0.246

TNR (%)

110,205/110,213 (99.99)

4,119/4,120 (99.98)

0.753

110,022/110,071 (99.96)

4,100/4,101 (99.98)

0.822

110,240/110,240 (100)

4,125/4,125 (100)

1.000

109,948/110,005 (99.95)

4,081/4,083 (99.95)

0.785

PPV (%)

22/30 (73.33)

11/12 (91.67)

0.372

205/254 (80.71)

30/31 (96.77)

0.049

3/3 (100)

3/3 (100)

1.000

230/287 (80.14)

44/46 (95.65)

0.019

NPV (%)

110,205/110,256 (99.95)

4,119/4,120 (99.98)

0.781

110,022/110,032 (99.99)

4,100/4,101 (99.98)

0.865

110,240/110,283 (99.96)

4,125/4,129 (99.90)

0.158

109,948/109,999 (99.95)

4,081/4,086 (99.88)

0.031

  1. OFCs orofacial clefts, CLO cleft lip only, CLP cleft lip with cleft palate, CPO cleft palate only, TPR true positive rate, TNR true negative rate, PPV positive predictive value, NPV negative predictive value