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Table 1 Characteristics of Patients in the Training and Test Cohorts

From: Development and validation of a machine learning-derived radiomics model for diagnosis of osteoporosis and osteopenia using quantitative computed tomography

Characteristics

Training cohorts

Test cohorts

P

Osteoporosis

Osteopenia

P

Osteoporosis

Osteopenia

Gender, No. (%)

  

0.032*

  

0.897

Male

86 (28.40)

20 (18.00)

 

29 (22.50)

11 (23.40)

 

Female

217 (71.60)

91 (82.00)

 

100 (77.50)

36 (76.60)

 

Age, mean (SE), years

70.03 (0.55)

58.32 (0.92)

 < 0.001*

69.11 (0.85)

57.72 (1.45)

 < 0.001*

HGB, mean (SE), g/L

122.28 (1.67)

127.83 (1.59)

0.209

125.46 (1.54)

127.17 (2.60)

0.385

GLU, mean (SE), mmol/L

5.56 (0.07)

5.21 (0.13)

0.010*

5.80 (0.15)

5.28 (0.08)

0.010*

TBIL, mean (SE), umol/L

17.18 (3.83)

13.02 (0.59)

0.354

14.52 (0.69)

14.86 (0.89)

0.341

DBIL, mean (SE), umol/L

4.66 (0.91)

3.11 (0.13)

0.001

4.30 (0.35)

3.74 (0.34)

0.435

IBIL, mean (SE), umol/L

13.56 (3.95)

9.91 (0.49)

0.935

10.22 (0.45)

11.17 (0.70)

0.115

ALP, mean (SE), U/L

84.49 (1.50)

76.13 (2.40)

0.001*

85.06 (3.36)

75.84 (3.64)

0.153

UA, mean (SE), umol/L

301.77 (4.69)

305.54 (8.48)

0.851

307.97 (8.39)

296.66 (10.19)

0.351

Ca, mean (SE), mmol/L

2.64 (0.34)

2.34 (0.01)

0.001

2.29 (0.01)

2.33 (0.02)

0.049*

Mg, mean (SE), mmol/L

1.06 (0.01)

1.04 (0.02)

0.968

1.07 (0.02)

1.01 (0.02)

0.062

P, mean (SE), mmol/L

1.09 (0.01)

1.13 (0.02)

0.047*

1.09 (0.01)

1.10 (0.02)

0.858

HCY, mean (SE), umol/L

14.83 (0.58)

11.48 (0.50)

 < 0.001*

14.90 (0.86)

12.83 (0.71)

0.252

  1. P value is derived from the univariable association analyses. Chi-Square was used to analyze the difference of categorical data (Gender), while the independent sample t-test or Mann–Whitney U test was used to analyze the difference of quantitative data (Age, HGB, GLU, TBIL, DBIL, IBIL, ALP, UA, Ca, Mg, P, HCY)
  2. HGB hemoglobin, GLU glucose, TBIL total bilirubin, DBIL direct bilirubin, IBIL indirect bilirubin, ALP alkaline phosphatase, UA uric acid, Ca calcium, Mg magnesium, P phosphorus, HCY homocysteine, SE standard error
  3. *P value < 0.05