Saturation-pulse prepared heart-rate independent inversion-recovery (SAPPHIRE) biventricular T1 mapping: inter-field strength, head-to-head comparison of diastolic, systolic and dark-blood measurements

Table 3 Summary of LV T₁ mapping data by MOLLI and the 4 SAPPHIRE variants across field strengths

Sequence	Field Strength	Basal SAX	Mid SAX	Apical SAX	Mid Septal ROI	Global T₁	Non-apical Global T₁
MOLLI*	1.5 T	1032 ± 23	1029 ± 26	1030 ± 21	1037 ± 28	1034 ± 7	1031 ± 2
	3 T	1297 ± 27	1297 ± 26	1311 ± 32	1310 ± 36	1298 ± 9	1295 ± 3
Diastolic SAPPHIRE	1.5 T	1261 ± 45	1267 ± 33	1342 ± 60	1250 ± 79	1284 ± 11	1264 ± 3
	3 T	1637 ± 83	1596 ± 48	1593 ± 70	1603 ± 53	1601 ± 17	1612 ± 6
Systolic SAPPHIRE	1.5 T	1286 ± 51	1225 ± 21	1239 ± 18	1225 ± 42	1239 ± 9	1253 ± 5
	3 T	1580 ± 41	1586 ± 44	1596 ± 43	1585 ± 48	1596 ± 13	1591 ± 4
DB 0th order SAPPHIRE	1.5 T	1229 ± 57	1248 ± 30	1246 ± 55	1228 ± 78	1241 ± 10	1242 ± 3
	3 T	1571 ± 69	1595 ± 46	1608 ± 42	1597 ± 74	1596 ± 12	1584 ± 5
DB 2nd order SAPPHIRE	1.5 T	1235 ± 46	1225 ± 61	1298 ± 51	1220 ± 111	1251 ± 11	1237 ± 5
	3 T	1550 ± 65	1555 ± 64	1569 ± 31	1503 ± 132	1561 ± 20	1561 ± 4

Values reported are mean ± 1SD
*At our CMR Unit (the UCL Bloomsbury Center for Clinical Phenotyping) normal values for native myocardial T₁ by MOLLI in healthy volunteers are 1030 ± 32 ms at 1.5 T and 1280 ± 46 ms at 3 T
DB, Dark blood; MOLLI, Modified Look-Locker inversion recovery; ROI, region of interest; SAPPHIRE, SAturation Pulse Prepared Heart-rate independent Inversion REcovery; SAX, short axis; T, Tesla. Other abbreviations as in Table 1

ISSN: 1471-2342