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Table 2 Mean DSC (SD) of AccuBrain IV2.0 and AccuBrain IV1.2 with manual hippocampal segmentation as reference method

From: Automated brain volumetric measures with AccuBrain: version comparison in accuracy, reproducibility and application for diagnosis

 

Left hippocampus

Right hippocampus

AccuBrain IV2.0

AccuBrain IV1.2

p

AccuBrain IV2.0

AccuBrain IV1.2

p

All (n = 135)

0.910 (0.016)

0.892 (0.026)

< 0.001

0.912 (0.018)

0.890 (0.033)

< 0.001

Diagnosis

      

 NC (n = 45)

0.919 (0.015)

0.907 (0.019)

< 0.001

0.921 (0.012)

0.904 (0.018)

< 0.001

 MCI (n = 45)

0.910 (0.013)

0.889 (0.020)

< 0.001

0.913 (0.015)

0.889 (0.029)

< 0.001

 AD (n = 45)

0.902 (0.016)

0.880 (0.030)

< 0.001

0.903 (0.021)

0.877 (0.041)

< 0.001

Field strength

      

 1.5T (n = 68)

0.916 (0.014)

0.894 (0.026)

< 0.001

0.913 (0.019)

0.890 (0.039)

< 0.001

 3.0T (n = 67)

0.905 (0.017)

0.890 (0.026)

< 0.001

0.911 (0.016)

0.890 (0.025)

< 0.001

Manufacturer

      

 GE (n = 45)

0.912 (0.014)

0.894 (0.026)

< 0.001

0.916 (0.013)

0.900 (0.023)

< 0.001

 Philips (n = 44)

0.914 (0.015)

0.893 (0.023)

< 0.001

0.916 (0.016)

0.888 (0.028)

< 0.001

 S (n = 46)

0.905 (0.018)

0.889 (0.028)

< 0.001

0.905 (0.021)

0.882 (0.042)

< 0.001

  1. The significance levels (p) of the paired sample tests for the entire cohort and specific sub-cohorts are displayed
  2. DSC Dice similarity coefficient, NC normal control, MCI mild cognitive impairment, AD Alzheimer’s disease
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BMC Medical Imaging

ISSN: 1471-2342

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