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Table 1 Baseline characteristics of the groups (n = 253)

From: Evaluation of liver fibrosis in chronic hepatitis B patients with 2D shear wave elastography with propagation map guidance: a single-centre study

 

Group 1 (n = 129)

Group 2 (n = 124)

p value

Age (years)

35.5 (26.0–44.0)

33.7 (25.0–41.0)

0.282

Gender (male)

69 (53.5)

70 (56.5)

0.746

Laboratory values

   

 HBV DNA (IU/ml)

405.5(35.0–567.0)

9.9 × 106(5.8 × 103–1.5 × 105)

< 0.001

 ALT

21 (17–28)

28 (19–41)

< 0.001

 AST

20 (17–24)

28 (19–30)

< 0.001

 Platelet (109/L)

257 (215–296)

218 (196–246)

0.002

 INR

1.12 (1.08–1.19)

1.10 (1.05–1.16)

0.155

 PT (s)

12.0 (11.5–12.6)

11.8 (11.2–12.5)

0.581

 PTT (s)

29.6 (28.4–31.4)

30.2 (28.6–32.1)

0.041

Biochemical scoring

   

 FIB-4

0.57 (0.43–0.75)

0.75 (0.44–0.96)

0.227

 APRI

0.22 (0.17–0.28)

0.35 (0.20–0.47)

< 0.001

Liver diameter (mm)

   

 Right lobe

146.0 (140.0–153.0)

147.0 (140.0–155.0)

0.412

 Left lobe

70.0 (64.0–79.0)

70.0 (65.0–77.0)

0.717

 Spleen diameter (mm)

109.0 (101.0–118.0)

111.5 (102.0–120.0)

0.464

2D-SWE, LSM

   

 kPa

6.2 (5.6–6.7)

8.15 (6.8–9.4)

< 0.001

 m/s

1.41 (1.34–1.49)

1.59 (1.48–1.83)

< 0.001

  1. Quantitative data were expressed as median (25–75% quartiles) and qualitative data were expressed as number and percentage (%)
  2. Group1 HBeAg negative chronic infection carriers, Group 2 HBeAg negative or positive chronic hepatitis and HBeAg positive chronic inection patients, ALT Alanine aminotransferase, AST Aspartate aminotransferase, INR International normalized ratio, PT Prothrombin time, PTT Partial thromboplastin time, FIB-4 Fibrosis 4, APRI AST-to platelet ratio index, 2D-SWE Two dimensional share wave elastography, LSM Liver stiffness measurement